Structure of PDB 5cky Chain O Binding Site BS01

Receptor Information
>5cky Chain O (length=324) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDLLKNLLTMGVDIDMARKRQPGVFHRMITNEQDLKMFLLSKGASKEVIA
SIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILEASPESFFRSNN
NLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAG
LSLGHNDPADFVRKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLV
LICGPGAEILDLSNDYARRSYANIKEKLFSLGCTEEEVQKFVLSYPDVIF
LAEKKFNDKIDCLMEENISISQIIENPRVLDSSISTLKSRIKELVNAGCN
LSTLNITLLSWSKKRYEAKLKKLS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5cky Base Flipping by MTERF1 Can Accommodate Multiple Conformations and Occurs in a Stepwise Fashion.
Resolution2.62 Å
Binding residue
(original residue number in PDB)		R92 R127 A162 S163 E165 T198 N199 R202 R350 N377 T379 K391 K394
Binding residue
(residue number reindexed from 1)		R20 R55 A90 S91 E93 T126 N127 R130 R278 N305 T307 K319 K322
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003690 double-stranded DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5cky, PDBe:5cky, PDBj:5cky
PDBsum5cky
PubMed26523681
UniProtQ99551|MTEF1_HUMAN Transcription termination factor 1, mitochondrial (Gene Name=MTERF1)

[Back to BioLiP]