Structure of PDB 4ui9 Chain O Binding Site BS01

Receptor Information
>4ui9 Chain O (length=685) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KDWVTPYKIAVLVLLSEMSRTGEGAVSLVERRRLNQQLLPLLQGPDITVS
KLLKLIEESCPQLANSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEV
HKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQSDENKKPLSQKQA
EFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNL
RVQDVFSSTHSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHC
RFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLE
HSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKH
SLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLEQQNNTESFAV
ALCHLAELHAEQGCFAAASEVLKHLKERFPPNSQHAQLWMLCDQKIQFDR
AMNDGKYHLADSLVTGITALNSIEGVYRKAVVLQAQNQMSEAHKLLQKLL
VHCQKLKNTEMVISVLLSVAELYWRSSSPTIALPMLLQALALSKEYRLQY
LASETVLNLAFAQLILGIPEQALSLLHMAIEPILADGAILDKGRAMFLVA
KCQVASAASYDQPKKAEALEAAIENLNEAKNYFAKVDCKERIRDVVYFQA
RLYHTLGKTQERNRCAMLFRQLHQELPSVPLINHL
Ligand information
>4ui9 Chain U (length=24) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MSRRPCSCALRPPAAAAAAAAAAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4ui9 Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Y715 R730 N731 F737 R738
Binding residue
(residue number reindexed from 1)		Y647 R662 N663 F669 R670
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005680 anaphase-promoting complex

View graph for
Cellular Component
External links
PDB RCSB:4ui9, PDBe:4ui9, PDBj:4ui9
PDBsum4ui9
PubMed26083744
UniProtQ9UJX4|APC5_HUMAN Anaphase-promoting complex subunit 5 (Gene Name=ANAPC5)

[Back to BioLiP]