Structure of PDB 4kzz Chain O Binding Site BS01

Receptor Information
>4kzz Chain O (length=136) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLGPQVAEGENVFGVCHIFASFNDTFVHVTDLSGKETICRVTGGMKVKAD
RDESSPYAAMLAAQDVAQRCKELGITALHIKLRATGGNRTKTPGPGAQSA
LRALARSGMKIGRIEDVTPIPSDSTRRKGGRRGRRL
Ligand information
>4kzz Chain i (length=1797) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucuccuacuuggauaa
cugugguaauucuagagcuaauacaugccgacggcgcugacucccuuugu
gugggaugcgugcauuuaucagaucaaaaccaacccggucagccuccccg
ccggccggggggguggggcggcggcuuuggugacucuagauaaccucggg
ccgaucgcagcccuccguggcggcgacgacccauucgaacgucugcccua
ucaacuuucgaugguagucgccgugccuaccauggugaccacgggugacg
gggaaucaggguucgauuccggagagggagccugagaaacggcuaccaca
uccaaggaaggcagcaggcgcgcaaauuacccacucccgacccggggagg
uagugacgaaaaauaacaauacaggacucuuucgaggcccuguaauugga
augaguccacuuuaaauccuuuaacgaggauccauuggagggcaagucug
gucgcagcagccgcgguaauuccagcuccaauagcguauauuaaaguugc
ugcaguuaaaaagcucguaguuggaucuuggagggugcguagcgggccac
cgcccguccccgcccugccuccgaagcguuuacuuugaaaaaauuagagu
guucaaagcaggcccgagccgccuggauaccgcagcuaggaauaauggaa
uaggaccgcgguucuauuuuguugguuuucggaacugaggccaugauuaa
gagggacggccgggggcauucguauugcgccgcuagaggugaaauucuug
gaccggcgcaagacggaccagagcgaaagcauuugccaagaauguuuuca
uuaaucaagaacgaaagucggagguucgaagacgaucagauaccgucgua
guuccgaccauaaacgaugccgacuggcgaugcggcggcguuauucccau
gacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgggggga
guaugguugcaaagcugaaacuuaaaggaauugacggaagggcaccacca
ggaguggagccugcggcuuaauuugacucaacacgggaaaccucacccgg
cccggacacggacaggauugacagauugauagcucuuucucgauucugug
ggugguggugcauggccguucuuaguugguggagcgauuugucugguuaa
uuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgacccccg
agcggucggcgucccccaacuucuuagagggacaaguggcguucagccac
ccgagauugagcaauaacaggucugugaugcccuuagaugucggggcugc
acgcgcgcuacacugacuggcucagcgugugccuacccuacgccggcagg
cgcggguaacccguugaaccccauucgugauggggaucggggauugcaau
uauuccccaugaacgaggaauucccaguaagugcgggucauaagcuugcg
uugauuaagucccugcccuuuguacacaccgcccgucgcuacuaccgauu
ggaugguuuagugaggcccucggaucggcccgccggggucggcccacggc
ccuggcggagcgcugagaagacggucgaacuugacuaucuagaggaagua
aaagucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[....................<<.....
<<.<<<.....>>>.>>......>>.........<<<...<<.<......
>.>>...>>>.[[..(((((.....<<<<<<<<<<<<.<...<.<<<...
.......>..>.>.>.....>>>>..............)))))......]
]...<<<<.<<<......>>>.>>>>....]]]...}}....]]].<<<.
...<<<....<<<<<<<.........>>>>>>>>>>......>>>...<<
<.<<<<....>>>>....>>>.}}.<<.<<<..........>>>.>>.<.
<<....>>.>...]]]]]].........<<<....<<<.....>>>..>>
>......}}.......<<<<<<<<<.<<<....>>>.>.>>>>>.>>>..
....<<..<...........>..>>.........<<<<<((......<<<
<.....<<..))>>.......>>>>.>>>>>..)))))).]]].......
.....{{.......{{...[[[.[[....<..<<<...<..<........
>..>...>>>..>...<<.<...>.>>..<<<<<..<.......<<...<
.......>.<<<<.......>>>>...>>......>..>>..>>>.....
..[[....(((((((.....>>>>>>>>>.)))))))...]]....]]..
..<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>>>...
...>>>>>>>.>.>>.......<<....>>...>>>>..>..>>>.>>>.
..]]]...}}......<<<<<<<...<...<<<<.<.....>.>>>>...
>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<<......>
>>>>>>>>>.>..>>>...<<..}}>>...>>.....>>>.....<<<..
....<<<......>>>....>>>..]]]]..<<<<<.<<<<<<<..<<..
<<<<<..<<<.<<<<<<......<<........>>..........<<<<<
......<<<<<<.......<<.<<<........>>>.>>.....>>>>>>
.<.<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<....
..>>>...>>.>>>....<<<...<...<<<<..<<<<....<<<..<<<
<....>>>>.>>>....>>>>..>>>>..>.....<<<<<.....>>>>>
........>>>....>>>.>>>...>.>>>>>>>>.....>>>>>...>>
.>>>>.>>>.....<<.<<<........<.......<<<.<<<<....>>
>>.>>>....>.........>>>.>>............<<<<<.......
...>>>>>...........>>>>>.....<<<<<<<<.......>>>>>>
>>......>>...>>>>>>>>>>.>>.......<<.<..<<<<.<<....
<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<<<<<.....>>>>
>>>>>>.>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>
...>.>>.........<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4kzz The initiation of mammalian protein synthesis and mRNA scanning mechanism.
Resolution7.0305 Å
Binding residue
(original residue number in PDB)		N38 F41 H43 G49 K50 T52 M60 A64 D65 R66 E68 P134 I135 P136 S137 D138 S139 T140 R141 K143 G144 R146 R147 R149 R150
Binding residue
(residue number reindexed from 1)		N23 F26 H28 G34 K35 T37 M45 A49 D50 R51 E53 P119 I120 P121 S122 D123 S124 T125 R126 K128 G129 R131 R132 R134 R135
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4kzz, PDBe:4kzz, PDBj:4kzz
PDBsum4kzz
PubMed23873042
UniProtG1T1F0|RS14_RABIT Small ribosomal subunit protein uS11 (Gene Name=RPS14)

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