Structure of PDB 4csu Chain O Binding Site BS01

Receptor Information

>4csu Chain O (length=116) Species: 83333 (Escherichia coli K-12)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>4csu Chain A (length=115)

gcugcggccguagcgcgguggucccaccugaccccaugccgaacucagaa
gugaaacgccguagcgccgaugguaguguggggucuccccaugcgagagu
agggaacugccaggc

.<<<<<<.....<<<<<<<<....<<<<<<<.............>>>>..
>>>...>>>>>>.>>.<<.....<.<<<<<<<<...>>>>>>>>...>..
.>>...>>>>.>>..

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4csu Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase.
• Resolution: 5.5 Å
• Binding residue (original residue number in PDB): K3 R7 R15 H29 R30 T31 P32 R33 H34 Y36 Q38 G44 S45 E46 V47 V54 K56 K63 Y64 N67 K68 F97 Q98 H100 G101 R102 V103
• Binding residue (residue number reindexed from 1): K2 R6 R14 H28 R29 T30 P31 R32 H33 Y35 Q37 G43 S44 E45 V46 V53 K55 K62 Y63 N66 K67 F96 Q97 H99 G100 R101 V102

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4csu, PDBe:4csu, PDBj:4csu
• PDBsum: 4csu
• PubMed: 24844575
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)