Structure of PDB 3n2c Chain O Binding Site BS01

Receptor Information

>3n2c Chain O (length=408) Species: 32644 (unidentified) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TITVLQGGNVLDLERGVLLEHHHVVIDGERIVEVTDRPVDLPNAQAIDVR
GKTVMPGFIDCHVHVLASNANLGVNATQPNILAAIRSLPILDAMLSRGFT
SVRDAGGADWSLMQAVETGLVSGPRIFPSGKALSQTGGHGDFRPRGDLLE
PCSCCFRTGAIARVVDGVEGVRLAVREEIQKGATQIKIMASGGVASPTDP
IANTQYSEDEIRAIVDEAEAANTYVMAHAYTGRAIARAVRCGVRTIEHGN
LVDEAAAKLMHEHGAFVVPTLVTYDALAKHGAEFGMPPESVAKVASVQQK
GRESLEIYANAGVKMGFGSDLLGEMHAFQSGEFRIRAEVLGNLEALRSAT
TVAAEIVNMQGQLGVIAVGAIADLVVLDGNPLEDIGVVADEGARVEYVLQ
RGTLVKRQ

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

3n2c Chain O Residue 425 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3n2c Functional identification and structure determination of two novel prolidases from cog1228 in the amidohydrolase superfamily .
Resolution	2.81 Å
Binding residue (original residue number in PDB)	H63 H65 K188 D321
Binding residue (residue number reindexed from 1)	H62 H64 K187 D320
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0046872	metal ion binding

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:3n2c, PDBe:3n2c, PDBj:3n2c
PDBsum	3n2c
PubMed	20604542
UniProt	Q393A1

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