Structure of PDB 3mva Chain O Binding Site BS01

Receptor Information
>3mva Chain O (length=324) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDLLKNLLTMGVDIDMARKRQPGVFHRMITNEQDLKMFLLSKGASKEVIA
SIISRYPRAITRTPENLSKRWDLWRKIVTSDLEIVNILERSPESFFRSNN
NLNLENNIKFLYSVGLTRKCLCRLLTNAPRTFSNSLDLNKQMVEFLQAAG
LSLGHNDPADFVRKIIFKNPFILIQSTKRVKANIEFLRSTFNLNSEELLV
LICGPGAEILDLSNDYARRSYANIKEKLFSLGCTEEEVQKFVLSYPDVIF
LAEKKFNDKIDCLMEENISISQIIENPRVLDSSISTLKSRIKELVNAGCN
LSTLNITLLSWSKKRYEAKLKKLS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3mva Helix unwinding and base flipping enable human MTERF1 to terminate mitochondrial transcription.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		R92 R127 R162 E165 N199 K240 F243 R350 N377 T379 W383 K391
Binding residue
(residue number reindexed from 1)		R20 R55 R90 E93 N127 K168 F171 R278 N305 T307 W311 K319
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003690 double-stranded DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3mva, PDBe:3mva, PDBj:3mva
PDBsum3mva
PubMed20550934
UniProtQ99551|MTEF1_HUMAN Transcription termination factor 1, mitochondrial (Gene Name=MTERF1)

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