Structure of PDB 3h0g Chain O Binding Site BS01

Receptor Information
>3h0g Chain O (length=263) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVN
TSVMPDEFLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVEL
FLNAKCTGEGTMEIYARDLVVSSNSSLGHPILADPKSRGPLICKLRKEQE
ISLRCIAKKGIAKEHAKWSPTSAVAFEYDPWNKLQHTDYWFENDADAEWP
KSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPPNEIMVQGLRILQ
EKLAVLVRDLDEE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3h0g Chain O Residue 1269 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3h0g Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.
Resolution3.65 Å
Binding residue
(original residue number in PDB)		C96 C99
Binding residue
(residue number reindexed from 1)		C93 C96
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005665 RNA polymerase II, core complex
GO:0005829 cytosol
GO:0016591 RNA polymerase II, holoenzyme
GO:0055029 nuclear DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3h0g, PDBe:3h0g, PDBj:3h0g
PDBsum3h0g
PubMed19458260
UniProtP37382|RPB3_SCHPO DNA-directed RNA polymerase II subunit RPB3 (Gene Name=rpb3)

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