Structure of PDB 2z5s Chain O Binding Site BS01

Receptor Information
>2z5s Chain O (length=86) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTQVHPRAPLLQILKVAGAQEEVFTLKEVMHYLGQYIMMKQLYDKQRQHI
VHCHDDPLGELLEVGSFSVKNPSPVYEMLKRNLVIL
Ligand information
Receptor-Ligand Complex Structure
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PDB2z5s Molecular basis for the inhibition of p53 by Mdmx.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
M50 L53 G54 I57 M58 Q68 V89 P92 Y96
Binding residue
(residue number reindexed from 1)
M30 L33 G34 I37 M38 Q48 V69 P72 Y76
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process

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Cellular Component
External links
PDB RCSB:2z5s, PDBe:2z5s, PDBj:2z5s
PDBsum2z5s
PubMed17938582
UniProtQ7ZUW7|MDM4_DANRE Protein Mdm4 (Gene Name=mdm4)

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