Structure of PDB 2z5s Chain O Binding Site BS01
Receptor Information
>2z5s Chain O (length=86) Species:
7955
(Danio rerio) [
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GTQVHPRAPLLQILKVAGAQEEVFTLKEVMHYLGQYIMMKQLYDKQRQHI
VHCHDDPLGELLEVGSFSVKNPSPVYEMLKRNLVIL
Ligand information
>2z5s Chain R (length=10) Species:
9606
(Homo sapiens) [
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TFSDLWKLLP
Receptor-Ligand Complex Structure
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PDB
2z5s
Molecular basis for the inhibition of p53 by Mdmx.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
M50 L53 G54 I57 M58 Q68 V89 P92 Y96
Binding residue
(residue number reindexed from 1)
M30 L33 G34 I37 M38 Q48 V69 P72 Y76
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0043066
negative regulation of apoptotic process
GO:0051726
regulation of cell cycle
Cellular Component
GO:0005634
nucleus
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Biological Process
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Cellular Component
External links
PDB
RCSB:2z5s
,
PDBe:2z5s
,
PDBj:2z5s
PDBsum
2z5s
PubMed
17938582
UniProt
Q7ZUW7
|MDM4_DANRE Protein Mdm4 (Gene Name=mdm4)
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