Structure of PDB 7suk Chain NH Binding Site BS01

Receptor Information
>7suk Chain NH (length=1082) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LFKSNIFKLQIDELLEQVKLKQKHVLKVEKFLHKLYDILQEIPDWEEKSL
AEVDSFFKNKIVSVPFVDPKPIPQNTNYKFNYKKPDISLIGSFALKAGIY
QPNGSSIDTLLTMPKELFEKKDFLNFRCLHKRSVYLAYLTHHLLILLKKD
KLDSFLQLEYSYFDNDPLLPILRISCSKDYNFYKTRFSINLLIGFPYKVF
EPKKLLPNRNCIRILPATPLYNFSVLSSSTHENYLKYLYKTKKQTESFVE
ATVLGRLWLQQRGFSSNMSHSGSLGGFGTFEFTILMAALLNGGGINSNKI
LLHGFSSYQLFKGVIKYLATMDLCHDGHLQFHSNPASKYIDEGFQTPTLF
DKSTKVNILTKMTVSSYQILKEYAGETLRMLNNVVQDQFSNIFLTNISRF
DNLKYDLCYDVQLPLGKYNNLETSLAATFGSMERVKFITLENFLAHKITN
VARYALGDRIKYIQIEMVGQKSDFPITKRKVYSNTGGNHFNFDFVRVKLI
VNPSECDKLVTKGPAHSETMSTEAAVFKNFWGIKSSLRRFKDGSITHCCV
WSTSSSEPIISSIVNFALQKHVSKKAQISNETIKKFHNFLPLPNLPSSAK
TSVLNLSSFFNLKKSFDDLYKIIFQMKLPLSVKSILPVGSAFRYTSLCQP
VPFAYSDPDFFQDVILEFETSPKWPDEITSLEKAKTAFLLKIQEELSANS
STYRSFFSRDESIPYNLEIVTLNILTPEGYGFKFRVLTERDEILYLRAIA
NARNELKPELEATFLKFTAKYLASVRHTRTLENISHSYQFYSPVVRLFKR
WLDTHLLLGHITDELAELIAIKPFVDPAPYFIPGSLENGFLKVLKFISQW
NWKDDPLILDLVKPEERLTLAQYKGIQMNFTNLRNSDPNGTHLQFFVASK
NDPSGILYSSGIPLPIATRLTALAKVAVNLLQTHGLNQQTINLLFTPGLK
DYDFVVDLRTPIGLKSSCGILSAPSNFPENLNDLSEKMDPTYQLVKYLNL
KYKNSLILSSRKYIGVNGGEKGDKNVITGLIKPLFKGAHKFRVNLDCNVK
PVDDENVILNKEAIFHEIAAFGNDMVINFETD
Ligand information
>7suk Chain 8 (length=1192) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
agauaguuaucugguugauccugccaguagucauaugcuugucucagcca
ugcagcucauuaaaucaguuaucguuuauuugauagucaugguauaacug
ugguaauucuagagcuaaaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaauaacuuuucgaaucgcauggc
cuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgaug
guaggauaguggccuaccaugguuucaacggguaacggggaauaaggguu
cgauuccggagagggagccugagaaacggcuaccacauccaaggaagggc
aggcuuacccaauccuaauucagggagguagugacaauaaauaacgauac
agggcccauucgggucuuguaauuggaaugaguacaauguaaauaccuua
acgaggaacaauuggagggcaagucuggugccagcagccgcgguaauucc
agcuccaauagcguauauuagcucguaguugaacuauuaauagggacggu
cgggggcaucaguauucaauugucagaggugaaauucuuggauuuauuga
agacuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaaga
acgaaaguuaggggaucgaagaugaucagauaccgucguagucuuaagac
uagggaucgggugguguuuuuuuaaugacccacucggcaccuuacgagaa
aucaaagucuuuggguucuggggggaguauggucgcaaggcugaaacuua
aaggaauugacggaagggcaccaccaggaguggagccugcggcucaacac
ggggaaacucaccagguccagacacaauauuugugggugguggugcaugu
gaugcccuuguucuggcgcgcgcuacacugacggagccagcgagucuaac
cuuggccgagaggucuugguaaaaacuccgucggggaacgaggaauuccu
aguaagcgcaagucaucagcuugcguugauuacgucccugcccuuuguac
acaccgcccgucgcuaguaccgauugaauggcuuagugaggccucaggau
cugcuuagagaagggggcaacuccucucagagcggagauuuggacaaacu
uggucauuuagaggaacuaauuccguaggugaaccugcggaa
................................<<<<<<.....<..<<<.
<<<..<<<.......<<<..<<..<.....<<<..............<<.
.<<.....>>..>>............<<....>>...........<<<<.
..........<....>............>>>>...........<<...<<
.....>>..>>......>>>....>>>..>>>...<....<<<....<<<
<<<<<.......>>>>>>>>>>>......>......<<<...........
....>>>.>>>.<<.<<<..........>>>.>>.<.<<....>>.>.>>
>>>>..<<<....<<<.....>>>..>>>.......>.......<<<<<<
<.<<<<<....>>>>>.>>>.>>>>......<<..<...........>..
>>........<<<<<<<.......<<<....>>>................
..>>>>>>>.>>>>>>......<<..................<..<<<.<
<...<<<.......<<<<.......<<<......>>>..........>>>
>..........<<<....>>>...>>>..>>.>>>...>.........>>
..........<<........<...............>.....>>......
.<<<..<<<<<<<<.<<<........>>>>>>>>>>>..>>>........
........................................<<........
.>>.....<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<<.........
...........<<<<<......<<<<.....>>>>......<<<......
...>>>.....>>>>>>>>>.>>>.....<<<<<<<............<<
<..<<<<....>>>>..>>>.....>>>>>>>............>>>>>>
....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>.....
.......>>>>>..<<<<.<<....<<<<<<<<.<<<....<<......<
<<<<<<.<<<<.<.<......>>.>>>>.>>>>>>>.....>>....>>>
.>>>>>>>>...>>.>>>>..<<<<<<<<....>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7suk Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome.
Resolution3.99 Å
Binding residue
(original residue number in PDB)		K217 N311
Binding residue
(residue number reindexed from 1)		K121 N208
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006364 rRNA processing
GO:0006409 tRNA export from nucleus
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0060962 regulation of ribosomal protein gene transcription by RNA polymerase II
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0032545 CURI complex
GO:0034456 UTP-C complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7suk, PDBe:7suk, PDBj:7suk
PDBsum7suk
PubMed35650250
UniProtP53254|UTP22_YEAST U3 small nucleolar RNA-associated protein 22 (Gene Name=UTP22)

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