Structure of PDB 7suk Chain NG Binding Site BS01

Receptor Information

>7suk Chain NG (length=111) Species: 4932 (Saccharomyces cerevisiae)

NSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYA
AMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSG
LRIGRIEDVTP

Ligand information

>7suk Chain 8 (length=1192)

agauaguuaucugguugauccugccaguagucauaugcuugucucagcca
ugcagcucauuaaaucaguuaucguuuauuugauagucaugguauaacug
ugguaauucuagagcuaaaaucucgacccuuuggaagagauguauuuauu
agaucaaugucuucggacucuuugaugaauaacuuuucgaaucgcauggc
cuugugcuggcgaugguucauucaaauuucugcccuaucaacuuucgaug
guaggauaguggccuaccaugguuucaacggguaacggggaauaaggguu
cgauuccggagagggagccugagaaacggcuaccacauccaaggaagggc
aggcuuacccaauccuaauucagggagguagugacaauaaauaacgauac
agggcccauucgggucuuguaauuggaaugaguacaauguaaauaccuua
acgaggaacaauuggagggcaagucuggugccagcagccgcgguaauucc
agcuccaauagcguauauuagcucguaguugaacuauuaauagggacggu
cgggggcaucaguauucaauugucagaggugaaauucuuggauuuauuga
agacuaacuacugcgaaagcauuugccaaggacguuuucauuaaucaaga
acgaaaguuaggggaucgaagaugaucagauaccgucguagucuuaagac
uagggaucgggugguguuuuuuuaaugacccacucggcaccuuacgagaa
aucaaagucuuuggguucuggggggaguauggucgcaaggcugaaacuua
aaggaauugacggaagggcaccaccaggaguggagccugcggcucaacac
ggggaaacucaccagguccagacacaauauuugugggugguggugcaugu
gaugcccuuguucuggcgcgcgcuacacugacggagccagcgagucuaac
cuuggccgagaggucuugguaaaaacuccgucggggaacgaggaauuccu
aguaagcgcaagucaucagcuugcguugauuacgucccugcccuuuguac
acaccgcccgucgcuaguaccgauugaauggcuuagugaggccucaggau
cugcuuagagaagggggcaacuccucucagagcggagauuuggacaaacu
uggucauuuagaggaacuaauuccguaggugaaccugcggaa

................................<<<<<<.....<..<<<.
<<<..<<<.......<<<..<<..<.....<<<..............<<.
.<<.....>>..>>............<<....>>...........<<<<.
..........<....>............>>>>...........<<...<<
.....>>..>>......>>>....>>>..>>>...<....<<<....<<<
<<<<<.......>>>>>>>>>>>......>......<<<...........
....>>>.>>>.<<.<<<..........>>>.>>.<.<<....>>.>.>>
>>>>..<<<....<<<.....>>>..>>>.......>.......<<<<<<
<.<<<<<....>>>>>.>>>.>>>>......<<..<...........>..
>>........<<<<<<<.......<<<....>>>................
..>>>>>>>.>>>>>>......<<..................<..<<<.<
<...<<<.......<<<<.......<<<......>>>..........>>>
>..........<<<....>>>...>>>..>>.>>>...>.........>>
..........<<........<...............>.....>>......
.<<<..<<<<<<<<.<<<........>>>>>>>>>>>..>>>........
........................................<<........
.>>.....<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<<.........
...........<<<<<......<<<<.....>>>>......<<<......
...>>>.....>>>>>>>>>.>>>.....<<<<<<<............<<
<..<<<<....>>>>..>>>.....>>>>>>>............>>>>>>
....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>.....
.......>>>>>..<<<<.<<....<<<<<<<<.<<<....<<......<
<<<<<<.<<<<.<.<......>>.>>>>.>>>>>>>.....>>....>>>
.>>>>>>>>...>>.>>>>..<<<<<<<<....>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7suk Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome.
• Resolution: 3.99 Å
• Binding residue (original residue number in PDB): D25 F27 H29 V30 G35 T38 A40 R41 G44 G45 D51 P120
• Binding residue (residue number reindexed from 1): D16 F18 H20 V21 G26 T29 A31 R32 G35 G36 D42 P111

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome

External links

• PDB: RCSB:7suk, PDBe:7suk, PDBj:7suk
• PDBsum: 7suk
• PubMed: 35650250
• UniProt: P06367|RS14A_YEAST Small ribosomal subunit protein uS11A (Gene Name=RPS14A)