Structure of PDB 9gaw Chain N Binding Site BS01

Receptor Information

>9gaw Chain N (length=632) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GQELLVAWNTVSTGLVPPPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQ
NDLQANISPEFWNAISQCENSADEPQCLLLLLDAFGLLESRLDPYLRSLE
LLEKWTRLGLLMGTGAQGLREEVHTMLRGVLFFSTPRTFQEMIQRLYGCF
LRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCSSDKQQ
CWCRQALEQFHQLSQVLHRLSLLERVSAEAVTTTLHQVTRERMEDRCRGE
YERSFLREFHKWIERVVGWLGKVFLQGNTLRRWRCHVQRFFYRIYASLRI
EELFSIVRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKAALETRLLHPGV
NTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAG
LTGDSDGTGDLAVELSKTDGEPEDWVPDPVDARRSSDIISLLVSIYGSKD
LFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKD
MADSRRINANIREEDEKRPAEEQPPFGVYAVILSSEFWPPFKDEKLEVPE
DIRAALEAYCKKYEQLKAMRTLSWKHTLGLVTAVTPVQAVILLYFQWTLE
ELSKAVKMPVALLRRRMSVWLQQGVLRTFSVI

Ligand information

Ligand ID

InChI

InChI=1S/Zn/q+2

InChIKey

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Name

ZINC ION

PDB chain

9gaw Chain N Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	9gaw High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
Resolution	2.9 Å
Binding residue (original residue number in PDB)	C221 C224 C231 C233
Binding residue (residue number reindexed from 1)	C191 C194 C201 C203
Annotation score	4

External links

PDB	RCSB:9gaw, PDBe:9gaw, PDBj:9gaw
PDBsum	9gaw
PubMed
UniProt	Q9UJX6\|ANC2_HUMAN Anaphase-promoting complex subunit 2 (Gene Name=ANAPC2)

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