Structure of PDB 8pk0 Chain N Binding Site BS01

Receptor Information
>8pk0 Chain N (length=144) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALLPASAGATEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFA
IWRVPAPFTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSRG
TLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTH
Ligand information
>8pk0 Chain A (length=1423) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggcucuuuggacac
uaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauaguaggc
cuaaaagcagccaccaauuaagaaagcguucaagcucaacacaaauccca
aacauauaacugaacuccucacacccaauuggaccaaucuaucacccuau
agaagaacuaauguuaguauaaguaacaugaaaacauucuccuccgcaua
agccugcgucagauuaaaacacugaacugacaauuaacagcccaauaucu
acaaucaaccaacaagucauuauuacccucacugucaacccaacacaggc
augcucauaaggaaagguuaaaaaaaguaaaaggaacucggcaaaucuua
ccccgccuguuuaccaaaaacaucaccucuagcaucaccaguauuagagg
caccgccugcuauauauauauauauauauauauauauauauuggcuccac
gaggguucagcugucucuuacuuuuaaccagugaaauugaccugcccgug
aggcgggcauaacacagcaagacgagaagacccuauggagcuuuaauuua
uuaaugcaaacagaaaccugcauuaaaaauuucgguuggggcgaccucgg
agcagaacccaaccuccgagcaguacaugcuaagacuucaccagucaaag
cgaacacucaauugauccaauaacuugaccaacggaacaaguuacccuag
ggacgcaauccuauucuagaguccauaucaacaauaggguuuuggaucag
gacaucccgauggugcagccgcuauuaaagguucguuuguucaacgauua
aaguccuacgugaucugaguucagaccggaguaauccaggucgguuucua
ucuacuuucaaauuccucccuguacgaaaggacaagagaaauaaggccua
cuucacaaagcgccuucccccguaaaugauaucaucucaacuuaguauac
ccaccccacccaagaacaggguu
<<<.......<<<<....................................
.<......>.........<.....<<.....>>....>........>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<...>>>>>>>>>..
.<<<......>>>....<<<.<<<...<..............<....<<<
.........>>>....>.......<<<......>>>..............
..........>...>>>>>>........>>>>>>...<<<<<......>>
>>>.........>>>>>><......<<..<<<....>>><<<<..<<<<.
.......<<<<<..............>>>>>......<<<...<<<<...
....................>>>>.......>>>.....<<......>>.
>>>>.....>>>>..<<<<...<<<<<<<<.<<................<
<<<<<..<<<.........>>>...<<<<<<.............>>>>>>
....<<<...<<<<<<..>>>>>>.<<<<<<<..>>>>>>>.>>>....>
>.>>>>........>>.>>>>>>>>>>>>.>>.....>.....<<<<<..
...>>>>>.......<<..<<<........<<<<<.<<<<<<..<<<<<.
<<<<<<<<..........>>>>>>>>>>>>>..<<<<.....>>>><<<<
<<...........>>>>>>..<<.....<<<..<<<<.....>>>>..>>
>.....>>.........<<<....>>>............>>>>..>>>>>
>>....<<<<<<<<<...<<.......>>...>>>>>>>>><<<<<.<<<
<<<..<<.<<<<<<......>>>>>>...>>.<<<<<.....>>>>>...
..>>>>>..>...>>>>>.....<<<<<<<....>>>.>>>>........
>>>.>>...<.<<<.<<<.................>>>.>>><<<<<...
<<<....>>>.>>>>>......<<<................>>>...>..
.......<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8pk0 Structural insights into the role of GTPBP10 in the RNA maturation of the mitoribosome.
Resolution3.03 Å
Binding residue
(original residue number in PDB)		K182 P184 V229 S231 P232 Y233
Binding residue
(residue number reindexed from 1)		K89 P91 V136 S138 P139 Y140
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8pk0, PDBe:8pk0, PDBj:8pk0
PDBsum8pk0
PubMed38042949
UniProtQ9NX20|RM16_HUMAN Large ribosomal subunit protein uL16m (Gene Name=MRPL16)

[Back to BioLiP]