Structure of PDB 8ow1 Chain N Binding Site BS01

Receptor Information
>8ow1 Chain N (length=386) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NELRLEDNYVPTSDTLVVFKQLMKLPVTVLYDLTLSWFAKFGGSFDGDIY
LLTETLDLLIEKGVRRNVIVNRILYVYWPDGLNVFQLAEIDCHLMISKPE
KFKWLPSKALRGDGKPYVVKLQPAKFIENLQTDLAKIYHCHVYMFKHPSL
PVLITRIQLFDSNKPLISRRPYYVAFPLNSPIIFHSVDKDIYARLVLQSI
SRTISERETIIFKPVQKIPVKSIHNIMTLLGPSRFAESMGPWECYASANF
ERSPLHDYKKHQGLTGKKVMVREFDDSFLNDGKEEPEIRRLRLEKNMIKF
KGSANGVMSRYSSLVPIEKVGFTLKNEINSRIITIKLKFNGNDIFGGLHE
LCDKNLINIDKVPGWLAGENGSFSGTIMNGDFQREQ
Ligand information
>8ow1 Chain D (length=153) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ataagtcacatggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaatattagtgta
tttgatttccgaaagttaaaaaagaaatagtaagaaatatatatttcatt
gaa
Receptor-Ligand Complex Structure
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PDB8ow1 Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
K105 K384
Binding residue
(residue number reindexed from 1)
K103 K319
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0007059 chromosome segregation
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0008608 attachment of spindle microtubules to kinetochore
GO:0034080 CENP-A containing chromatin assembly
GO:0034087 establishment of mitotic sister chromatid cohesion
GO:0034089 establishment of meiotic sister chromatid cohesion
GO:0034090 maintenance of meiotic sister chromatid cohesion
GO:0051301 cell division
GO:0051321 meiotic cell cycle
GO:0051382 kinetochore assembly
GO:0071459 protein localization to chromosome, centromeric region
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000940 outer kinetochore
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ow1, PDBe:8ow1, PDBj:8ow1
PDBsum8ow1
PubMed37506202
UniProtP38907|CENPN_YEAST Inner kinetochore subunit CHL4 (Gene Name=CHL4)

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