Structure of PDB 8g9s Chain N Binding Site BS01

Receptor Information
>8g9s Chain N (length=205) Species: 486 (Neisseria lactamica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RFILEISGDLACFTRSELKVERVSYPVITPAAARNILMAILWKPAIRWKV
LKIEILKPIQWTNIRRNEVGTKMSERSGSLYIEDNRQQRASMLLKDVAYR
IHADFDMTSEAGESDNYVKFAEMFKRRAKKGQYFHQPYLGCREFPCDFRL
LEKAEDGLPLEDITQDFGFMLYDMDFSKSDPRDSNNAEPMFYQCKAVNGV
ITVPP
Ligand information
>8g9s Chain O (length=42) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auugaaacagggucagcuugccguagguggcaucgcccucgu
..........................................
Receptor-Ligand Complex Structure
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PDB8g9s Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		T15 S17 K20 N36 N68 E69 V70 R87 Q89 P138 Y139 R143 F177
Binding residue
(residue number reindexed from 1)		T14 S16 K19 N35 N67 E68 V69 R86 Q88 P137 Y138 R142 F176
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8g9s, PDBe:8g9s, PDBj:8g9s
PDBsum8g9s
PubMed38242128
UniProtD0W8X4

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