Structure of PDB 8fru Chain N Binding Site BS01

Receptor Information
>8fru Chain N (length=203) Species: 941442 (Giardia intestinalis assemblage A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAYKYVQELWRKKQSEALHYLFRLRTWEYRQLNAIKRCSHPTRPEKARRL
GYKAKRGYVVYRVRVRRGGRKRQCVHGISYGKPRNIGIVGLKPSRSLRAL
AEQKVGRRLPSLRVLNSYWVAQDGSYKWYEVILIDPFHPWIRNDPKINWI
CNPVMKRRECRGLTSAGRKARGLHNKGIGAMKLRPSKRAAWKRNHTRSLR
RYR
Ligand information
>8fru Chain 4 (length=141) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aacgccccgccggcggaugccucggcccgggcggcgacgaagagcgcggc
ggagcgcgagacgcggugcggacccgcccgccccgagaagcaccggcccu
cgaacgcagcgcgccccggcgccgccgccucggugcccugc
.........................................<<<<<<.((
.....>>>.....<<<<<<...<..))..>.........>>>>>>...>>
>....<<...>><<....>>.....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8fru The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Resolution2.49 Å
Binding residue
(original residue number in PDB)		R38 R57 R109 L110 D136 H139
Binding residue
(residue number reindexed from 1)		R37 R56 R108 L109 D135 H138
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8fru, PDBe:8fru, PDBj:8fru
PDBsum8fru
PubMed38242118
UniProtA8B8Z6

[Back to BioLiP]