Structure of PDB 8caz Chain N Binding Site BS01

Receptor Information
>8caz Chain N (length=100) Species: 679895 (Escherichia coli BW25113) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNAVLKLQTL
PRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW
Ligand information
>8caz Chain A (length=460) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cccgcacaagcgguggagcaugugguuuaauucgaugcaacgcgaagaac
cuuaccuggucuugacauccacggaaguuuucagagaugagaaugugccu
ucgggaaccgugagacaggugcugcauggcugucgucagcucguguugug
aaauguuggguuaagucccgcaacgagcgcaacccuuauccuuuguugcc
agcgguccggccgggaacucaaaggagacugccagugauaaacuggagga
agguggggaugacgucaagucaucauggcccuuacgaccagggcuacaca
cgugcuacaauggcgcauacaaagagaagcgaccucgcgagagcaagcgg
accucauaaagugcgucguaguccggauuggagucugcaacucgacucca
ugaagucggaaucgcuaguaaucguggaucagaaugccacggugaauacg
uucccgggcc
<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>......
....<<<<<<<......<<<<<<<..<<<<<<<....>>>>>>>...<..
...>...>>>>>.>>.<<<.<<<..<<<<<<.......<<<<<<<<<...
.>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<...<<
..<<<.....>>>>>....>>>>>>>.....<<<<<.....>>>>>....
....>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>.>>
>>>>>>.....<<<<<<<.....<<<..<<...<<<....>>>...>>..
..>>>.....>>>>>>>......<....<<<<<<<........>>>>>>>
....>.....>>>>>>....<<<<<<<.........>>>>>>>......>
>...>>>>..
Receptor-Ligand Complex Structure
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PDB8caz Structural conservation of antibiotic interaction with ribosomes.
Resolution2.11 Å
Binding residue
(original residue number in PDB)		A2 K3 Q4 S5 M6 A8 R9 R13 K19 R24 K28 L48 Q49 R53 S56 S58 R59 R61 N62 R63 T67 R69 H71 G72 F73 R75 R81 I82 R85 K98 S100 W101
Binding residue
(residue number reindexed from 1)		A1 K2 Q3 S4 M5 A7 R8 R12 K18 R23 K27 L47 Q48 R52 S55 S57 R58 R60 N61 R62 T66 R68 H70 G71 F72 R74 R80 I81 R84 K97 S99 W100
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8caz, PDBe:8caz, PDBj:8caz
PDBsum8caz
PubMed37550453
UniProtP0AG59|RS14_ECOLI Small ribosomal subunit protein uS14 (Gene Name=rpsN)

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