Structure of PDB 8azw Chain N Binding Site BS01

Receptor Information
>8azw Chain N (length=142) Species: 4097 (Nicotiana tabacum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTVPGQLVWEIVKKNNSFLVKEFGNGTAGVVFSKEPNNLYNLHSYKHSGL
ANKKTVTIQAEGKDKSVLLATSKTKKQNKPSTLLNKSVMKKEFRRMSKAV
TNQVADNYYRPDLKKAALARLSAVNRSLKVAKSGVKKKNRQA
Ligand information
>8azw Chain A (length=3196) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcgaccccaggucaggcgggacuacccgcugaguuuaagcauaucaauaa
gcggaggaaaagaaacuuacaaggauuccccuaguaacggcgagcgaacc
gggaacagcccagccuuagaaucgggcggcuccgccguucgaauuguagu
cuggagaagcguccucagcggcggaccgggcccaaguccccuggaagggg
gcgccagagagggugagagccccguugugcccggacccugucgcaccacg
aggcgcugucuacgagucggguuguuugggaaugcagcccaaaucgggcg
gugaauuccguccaaggcuaaauacgggcgagagaccgauagcgaacaag
uaccgcgagggaaagaugaaaaggacuuugaaaagagagucaaagagugc
uugaaauugucgggagggaagcggaugggggccggcgaugcgccccgguc
ggauguggaacggugacgagccgguccgccgaucgacucggggcguggac
cagcguggauugggggggcggccaaagcccgggcuuucgauacgcccgug
gaacgccgucuccuugauugugguaggcagcgcgcgccuccggcgugcuu
cggcaucugcgcgcuccggacgcuggccugugggcuccccauucgacccg
ucuugaaacacggaccaaggagucugacaugugugcgagucaacgggcga
guaaacccguaaggcguaaggaagcugauuggugggaucccccugagggg
ugcaccgccgaccgaccuugaucuucugugaaggguucgagugugagcau
accugucgggacccgaaagauggugaacuaugccugagcggggcgaagcc
agaggaaacucugguggaggcccgcagcgauacugacgugcaaaucguuc
gucugacuuggguauaggggcgaaagacuaaucgaaccgucuaguagcug
guucccuccgaaguuucccucaggauagcuggagcucgcgugcgaguucu
aucggguaaagccaaugauuagaggcaucgggggcgcaacgcccucgacc
uauucucaaacuuuaaauagguaggacggugcggcugcuuuguugagccg
caccacggaaucaagagcuccaagugggccauuuuugguaagcagaacug
gcgaugcgggaugaaccggaagccggguuacggugccaaacugcgcgcua
accuagaucccacaaaggguguuggucgauuaagacagcgccgaaucaac
uagccccgaaaauggauggcgcuuaagcgcgcgaccuacacccggccguc
ggggcaagugccaggccccgaugaguaggagggcgcggcggucgcugcaa
aaccuugggcgcgagccugggcggagcggccgucggugcagaucuuggug
guaguagcaaauauucaaaugagaacuuugaaggccgaagaggggaaagg
uuccaugugaacggcacuugcacauggguuagucgauccuaagggucggg
ggaaccccgacagauagcgcguuucgcgcguacuccgaaagggaaucggg
uuaaaauuccugaaccgggacguggcgguugacggcaacguuaggaaguc
cggagacgucggcgggggccucgggaagaguuaucuuuucuguuuaacag
ccugcccacccuggaaacgacucagucggagguaggguccagcggcugga
agagcaccgcacgucgcgugguguccggugcgcccccggcggcccuugaa
aauccggaggaccgagugccguccacgcccggucguacucauaaccgcau
caggucuccaaggugaacagccucuggucgauggaacaauguaggcaagg
gaagucggcaaaauggauccguaacuucgggaaaaggauuggcucugagg
gcugggaacagccaacucagaacugguacggacaaggggaauccgacugu
uuaauuaaaacaaagcauugcgauggucccugcggauguuuacgcaaugu
gauuucugcccagugcucugaaugucaaagugaagaaauucaaccaagcg
cggguaaacggcgggaguaacuaugacucucuuaagguagccaaaugccu
cgucaucuaauuagugacgcgcaugaauggauuaacgagauucccacugu
cccugucuacuauccagcgaaaccacagccaagggaacgggcuuggcaga
aucagcggggaaagaagacccuguugagcuugacucuaguccgacuuugu
gaaaugacuugagaggguaguauaagugggagccggcgaaagugaaauac
cacuacuuuuaacguuauuuuacuuauuccgugaaucggaagcggggcac
ugccccucuuuuuggacccaaggcuugcuugcaggccgauccgggcggaa
gacauugucagguggggaguuuggcuggggcggcacaucuguuaaaagau
aacgcagguguccuaagaugagcucaacgagaacagaaaucucgugugga
acagaaggguaaaagcucguuugauucugauuuccaguacgaauacgaac
cgugaaagcguggccuaacgauccuuuagaccuucggaauucgaagcuag
aggugucagaaaaguuaccacagggauaacuggcuuguggcagccaagcg
uucauagcgacguugcuuuuugauccuucgaugucggcucuuccuaucau
ugugaagcagaauucaccaaguguuggauuguucacccaccaauagggaa
cgugagcuggguuuagaccgucgugagacagguuaguuuuacccuacuga
ugacagugucgcaauaguaauucaaccuaguacgagaggaaccguugauu
cgcacaauuggucaucgcgcuugguugaaaagccaguggcgcgaagcuac
cgugcgcuggauuaugacugaacgccucuaagucagaauccgggcuagaa
gcgacgcaugcgcccgccguccgcuugccgacccgcaguaggggccuuug
gcccccaagggcacgugucguuggcuaagucaucguggcggaagagccgc
gguggccgccuugaaguacaauuuccaucgagcggcggguagaauccuuu
gcagacgacuuaaauacgcgacgggguauuguaaguggcagaguggccuu
gcugccacgauccacugagauucagcccuuugucgcuccgauucgu
........................<<<<<<.....<......>......>
>>>>.>.........<<....>>..<<<<<.......<.....>......
>>>>>..[[[....<......<<<<<<<<<...>>>>>>>>>......>.
....<<<<<<<<.<<<.<<<<<<<.<<<<<<.<<...<<<<......>>>
>.((......<<<.....))>>>..>>.>>>>>>...>>>>>>>.....>
>>>>>>>.>>>.......<<<<<<<........>>>>>>>.....(((((
..<<<<<<)))))..]]]................................
..<<....>>...............<<<<....>>>>.............
.....................<<<<<<<<<<<<......<<<<<<<<<<<
<...<<<<<.<<<<.....>>>>.>>>>>....>>>>.>>>>>>>>.<.<
<<<<<..<<<<<<<<<<<<<<<.....<<<<<<<.........>>>>>.>
>...>>>>>>>>>>>>>>>.........<<<<<<<<<<...>>>..<<..
..>>....>>>>>>>.....>>>>>>.>....>>>.>>>>>>>>>..<<<
<........>>>><<<<<<.....<<<<<.<<<<<<..<<<...<<<...
.....>>>....>>>...<<....>>....<<<<<...<<<<....>>>>
....>>>>>.<<<<<<<.....<....>.....>>.>>>.>>....>>>>
>>.>>>>>...<<.<..<<<<<<<.....<<<<<<<<<..<<<....<<<
<<<<....>>>>>>>.....>>>...<<<<.<<.<<........>>>>>>
>>....>>>>>>>>>...<<.......>>......>>>>>>...>..>.>
>..<<<<<<....<.<<<....>>>.><<<<<<<<<<......<<.<<<<
<<<.....<<<....<<<....<<<....<<<<<<.....>>>>>>..>>
>....>>>..>.>>.....>>>>>...<<<<<<<<<.<......>>>>>>
>>>>....>>>>..>>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>
>>....<<<......>>>...<<<<<<<...<<<(((.....<<<<<<..
.....<..........<<<.<<<<<<.<<<.......<..>...>>>.>>
>>>>>>>..........))).>....>>>>>>.>>>...>>>>>>><<<<
<<<<<.........>>>>>>>>>....>>>>>><.<<<<<<<<<<.....
..<<<.<<<<....>>>>>>>....>>>>>>>>>>..>.....>>>>>><
<.....<<.....<<<<<<.......>>>>>><<<<.....<<<<<.<<.
..<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<....<<
<....>>>........<<<<<...>>>>>.....>>....>>...<<<<<
........>>>>>))<<<<.<<<<<<<<...<<<....>>>...<...<<
<<<<...<<<<.<<<<<<<.<<<<<.<<<<.......>>>>.><...<<<
<<.....<<<<<<....<<<<...>>>>....>>>>>>.....>>>>>..
..><<<<<<<.......>>>>>>>>>>>...>>>>>>>.>>>>.......
..>>>>>>...>......>>>>.>>>>>>>>>>>>..>>.....<<....
..>>>>>>>.<<<<.....>>>>..>>>>..<<<<.....<<<<<<<.<<
.........<.....<<<<<....<<..>>.....>>>>><<.<<<<<<<
<<<<....>>>>>..>>>>>>.>>............<<<<<<<<<..<<<
.........>>>..<<<<<<<....<<<<....>>>>......>>>>>>>
...<<..<<<..<<<<<<.<..<<<.....<<<<....>>>>.....>>>
>>>>>..>>>>><<<<<<.......>>>>>>........<..........
.<<<<<.......>>>>>.....>.....>>....>>.>>>>>>>..>..
>>.>>>>>>>..>>>>>>....>>....<<<<<........>>>>>....
[[[[[..{{{.{{......[[[[.{{[[[[..<<<<<.<<<.<<<...<<
<<<<<<<<.<<<<<<.........<<<<.<.<<<>>>............>
>>>>.>>>>>>..>>>>>>>>>>...<<<<<.....<<<<...<<<<<..
.>>>>>...............<<<<<<....>>>>>>..>>>>..>>>>>
......>>>.>>>..>>>>>...<<<.....>>>..<<<<<<........
...>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....
<<...(((>>....>>>>>>>...<<<.<<<<<.......>>>>.>>>>.
<<<....>>>.>>))).......((((((..((((.>>>>>>))))))))
))..........]]]]..}}]]]].......<<.<.<.<<<<<<...<<.
......>>...>>>>>>...>>.>.>.......<<<<<.<<<<<<..<<<
.<<<<<......>>>>>...>>>.<<<.........>>>.....>>>>>.
.>...>>>.>>....<<<<<<<....>>>.>>>>....}}..}}}.]]]]
]....<<<<<<<..<<<<.<.<<<<<.................>>>>>.>
<<<<<...<<<<....<<<<<<<<<......>>>>..>>>>>...>>>>.
.>>>>>.<<<<...<<<<<...........>>>>>...>>>>.>>>>...
>>>>>>>....<<<<<<<<<.<<.<......<<.......<<<<<<...>
>>>>>....>>...........<<<...<<<<<<<<<<<......>>>>>
>>>>>>.>>>................>.>>.>>>>>>>>>.<<<<<.<..
...........>.....<<<<<<<<<.<<<....<<<<.<..<<<<<...
...>>>>>..>>>>>...>>>....>>>>..>>>>>...>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8azw Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution.
Resolution2.14 Å
Binding residue
(original residue number in PDB)
W10 K15 N16 K22 G25 N26 H44 S45 Y46 K47 N53 K74 T75 K76 N86 V89 M90 K92 E93 A100 N103 Q104 R111 P112 D113 R127 K130 V131 S134 K137 K138 N140 R141 Q142
Binding residue
(residue number reindexed from 1)
W9 K14 N15 K21 G24 N25 H43 S44 Y45 K46 N52 K73 T74 K75 N85 V88 M89 K91 E92 A99 N102 Q103 R110 P111 D112 R126 K129 V130 S133 K136 K137 N139 R140 Q141
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8azw, PDBe:8azw, PDBj:8azw
PDBsum8azw
PubMed37156858
UniProtA0A1S4D1U6

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