Structure of PDB 8auv Chain N Binding Site BS01

Receptor Information
>8auv Chain N (length=69) Species: 4097 (Nicotiana tabacum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTYTKPKKIKHKKKKVKLAVLQFYKVDDSGKVQRLRKECPNAECGAGTFM
ANHFDRHYCGKCGLTYVYQ
Ligand information
>8auv Chain h (length=1626) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcauguguaaguaugaacaaauucagacugugaaacugcgaauggcuc
auuaaaucaguuauaguuuguuugaugguaucuacuacucggauaaccgu
aguaauucuagagcuaauacgugcaacaaaccccgacuucuggaagggau
gcauuuauuagauaugcgaugauucaugauaacucgacggaucgcacggc
cgccggcgacgcaucauucaaauuucugcccuaucaacuuucgaugguag
gauaguggccuaccaugguggugacgggugacggagaauuaggguucgau
uccggagagggagccugagaaacggcuaccacauccaaggaaggcagcag
gcgcgcaaauuacccaauccugacacggggagguagugacaauaaauaac
aauaccggcugguaauuggaaugaguacaaucuaaaucccuuaacgagga
uccauuggagggcaagucuggugccagcagccgcgguaauuccagcucca
auagcguauauuuaaguuguugcaguuaaaaagcucguaguuggacuuug
ggaugucccguuacuuugaagaaauuagagugcucaaagcaagccuacgc
ucuguauacauuagcaugggauaacauuauaggauuucgguccuauuucg
ggaucggaguaaugauuaacagggacagucgggggcauucguauuucaua
gucagaggugaaauucuuggauuuaugaaagacgaacaacugcgaaagca
uuugccaaggauguuuucauuaaucaagaacgaaaguugggggcucgaag
acgaucagauaccguccuagucucaaccauaaacgaugccgaccagggau
cggcggauguugcuaggacuccgccggcaccuuaugagaaaucaaaguuu
uuggguuccggggggaguauggucgcaaggcugaaacuuaaaggaauuga
cggaagggcaccaccaggaguggagccugcggcuuaauuugacucaacac
ggggaaacuuaccagguccagacauaguaaggauugacagacugagagcu
cuuucuugauucuaugggugguggugcauggccguucuuaguugguggag
cgauuugucugguuaauuccguuaacgaacgagaccucagccugcuaacu
agcuaugcggagguaucccuucgcggccagcuucuuagagggacuacggc
cuuuuaggccgcggaaguuugaggcaauaacaggucugugaugcccuuag
auguucugggccgcacgcgcgcuacacugauguauucaacgaguuuauag
ccuuggccgacaggcccggguaaucuuugaaauuucaucgugauggggau
agaucauugcaauuguuggucuucaacgaggaauuccuaguaagcgcgag
ucaucagcucgcguugacuacgucccugcccuuuguacacaccgcccguc
gcuccuaccgauugaaugauccggugaaauguucggaucgcgcgagaagu
ccauugaaccuuaucauuuagaggaaggagaagucguaacaagguuuccg
uaggugaaccugcggaaggaucauug
...<<<<<.[.((((>>>>>.<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<...........>>...>>.>>......<<.
.......<<<..<<..<<....<<<<<............<<.....<..<
<<.....>>>..>......>>........<.<<<..<<...>>..>>>.>
....<<<<<<................>>>>>>.........<<<<.<<<<
.>>>>>>>>..>>>>>...>>>>..>>>.<<<....<<<....<<<<<<<
<.......>>>>>>>>>>>......>>>...<<<.<<<<....>>>>...
.>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>
>>.........<<<....<<<.....>>>..>>>..>....>.>.....<
<<<<<<<..>>>>>.>>>......<<..<...........>..>>.....
....<<<<<((....<.<<<<.....<<..))>>.......>>>>>>>>>
>..>>>>>>>>>..........<.<((.....<.<<...<<<.<<.....
<<<..>>>.<<<<<<.<<.......<<...<.......>..<<<....>>
>.....>>......>>.>>..>>>>........<<<<<<<<<<<.....>
>>>>>>>>>>.....>>....<<<<<<.<<...<<<<..<<..<<<<<<<
<...<<<......>>>......>>>>>>>>..>>.......<<....>>.
..>>>>...>>>>>.>>>...>>>...>>.>....<<<<<<<...<...<
<<<.........>>>>...>>>>>>>>..........<<<.<<.<<<..<
<<<<<<<.<<<.<..>>>>>>>>>>>>..>>>...<<..))>>...>>..
...>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]<<<
<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<.......<<........>
>..........<<<<<......<<<<<........<<.<<<........>
>>.>>......>>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<..
....>>...<<<......>>>...>>.>>>....<<<<<.<<..<<<<..
<<<<.<<<<<<<<....>>>>>>>>...>>>>..>>>>.>>.....<<<<
<.....>>>>>........>>>>>....>>>.>>>.....>>>>>>>...
....>>>>>....>.>>>>.>>>.....<<<<.<.......<<.......
<<<.<<<<....>>>>.>>>....>>.......>.>>>>......<....
<<<<<<..........>>>>>>....>.....>>>>>>....<<<<<<<<
.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
.<<<<<.<<....<<<<<<<..<<<..<<<<..<...<<<<>>>>...>.
.>>>>..>>>..>>>>>>>...>>.>>>>>..>.>>...>.....<<<<<
<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
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PDB8auv Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution.
Resolution2.38 Å
Binding residue
(original residue number in PDB)		K83 Y85 K89 K90 K92 H93 K95 K96 K97 K99 L100 F105 R118 F131 A133 H135 R138 Y140 G142 K143 T147
Binding residue
(residue number reindexed from 1)		K1 Y3 K7 K8 K10 H11 K13 K14 K15 K17 L18 F23 R36 F49 A51 H53 R56 Y58 G60 K61 T65
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0031386 protein tag activity
GO:0031625 ubiquitin protein ligase binding
Biological Process
GO:0006412 translation
GO:0016567 protein ubiquitination
GO:0019941 modification-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8auv, PDBe:8auv, PDBj:8auv
PDBsum8auv
PubMed37156858
UniProtA0A1S4C0C1

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