Structure of PDB 7yyh Chain N Binding Site BS01

Receptor Information
>7yyh Chain N (length=297) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQH
LIHLCEEKRASISDAALLDIIYMQFHQHQKVWEVFQMSKDLFDMKQFKNS
FKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPTYVVYYSQ
TPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDSLKAIVFK
QYMDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQYKLETKFKSEPL
RCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYFKIRD
Ligand information
>7yyh Chain J (length=153) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ttggaccgctttgaggccttcgttggaaacgggaatatcttcacataaaa
actaaacagaagcattctcagaaacttctttgtgatgattgcattcaact
cacagagttgaacattccttttgatagagcagttttgaaacactcttttt
gta
Receptor-Ligand Complex Structure
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PDB7yyh Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Resolution8.9 Å
Binding residue
(original residue number in PDB)		M18 R44 K45 M167 R169
Binding residue
(residue number reindexed from 1)		M17 R43 K44 M160 R162
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:7yyh, PDBe:7yyh, PDBj:7yyh
PDBsum7yyh
PubMed35420891
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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