Structure of PDB 7xho Chain N Binding Site BS01

Receptor Information
>7xho Chain N (length=305) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDETVAEFIKRTILKIPMNELTTILKAWDFLSENQLQTVNFRQRKESVVQ
HLIHLCEEKRASISDAALLDIIYMQFHQHQKVWDVFQMSKGPGEDVDLFD
MKQFKNSFKKILQRALKNVTVSFRETEENAVWIRIAWGTQYTKPNQYKPT
YVVYYSQTPYAFTSSSMLRRNTPLLGQALTIASKHHQIVKMDLRSRYLDS
LKAIVFKQYNQDSRIIHENIVEKERVQRITQETFGDYPQPQLEFAQYKLE
TKFKEPLRCLIKFSSPHLLEALKSLAPAGIADAPLSPLLTCIPNKRMNYF
KIRDK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7xho Structural insights into human CCAN complex assembled onto DNA.
Resolution3.29 Å
Binding residue
(original residue number in PDB)		Q268 Y269 K270 L271 E272 L322 F334 K335 I336 R337 D338 K339
Binding residue
(residue number reindexed from 1)		Q246 Y247 K248 L249 E250 L288 F300 K301 I302 R303 D304 K305
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007059 chromosome segregation
GO:0034080 CENP-A containing chromatin assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0000939 inner kinetochore
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xho, PDBe:7xho, PDBj:7xho
PDBsum7xho
PubMed36085283
UniProtQ96H22|CENPN_HUMAN Centromere protein N (Gene Name=CENPN)

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