Structure of PDB 7tr9 Chain N Binding Site BS01

Receptor Information
>7tr9 Chain N (length=321) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MYVRISGRIRLNAHSLNAQGGGGTNYIEITKTKVTVRTENGWTVVEVPAI
TGNMLKHWHFVGFVDYFKTTPYGVNLTERALRYNGTRFGQGETTATKANG
ATVQLNDEATIIKELADADVHGFLAPKTGRRRVSLVKASFILPTEDFIKE
VEGERLITAIKHNRTAQMLFSREYATGLYGFSIVLDLGLVGIPQGLPVKF
EENQPRPNIVIDPNERKARIESALKALIPMLSGYIGANLARSFPVFKVEE
LVAIASEGPIPALVHGFYEDYIEANRSIIKNARALGFNIEVFTYNVDLGE
DIEATKVSSVEELVANLVKMV
Ligand information
>7tr9 Chain R (length=45) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auugaaagagugcuuccccaaacccuuaacugguuguaacaguug
.............................................
Receptor-Ligand Complex Structure
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PDB7tr9 Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		A18 Q19 G20 N53 M54 K56 H57 W58 G85 R87 H121 L124 R131 V133 S134 N163 R164 F185 A252 N253 R256
Binding residue
(residue number reindexed from 1)		A18 Q19 G20 N53 M54 K56 H57 W58 G85 R87 H121 L124 R131 V133 S134 N163 R164 F170 A237 N238 R241
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Biological Process
External links
PDB RCSB:7tr9, PDBe:7tr9, PDBj:7tr9
PDBsum7tr9
PubMed35835111
UniProtQ8U333

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