Structure of PDB 7ods Chain N Binding Site BS01

Receptor Information
>7ods Chain N (length=209) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VKTLLPVPSFEDVSIPEKPKLRFIERAPLVPKVRREPKNLSDIRGPSTEA
TEFTEGNFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFAIWRVPAPFK
PITRKDHYVTPVKAGRLVVEMGGRCEFEEVQGFLDQVAHKLPFAAKAVSR
GTLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVLSPYDLTHKGKYW
GKFYMPKRV
Ligand information
>7ods Chain A (length=1445) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccagacaaccuuagc
caaaccauuuacccaaauaaaguauaggcgauagaaauugaaaccuggcg
caauagauauaguaccgcaagggaaagaugaaaaauuauaaccaagcaua
auauagcaaggacuaaccccuauaccuucugcauaaugaauuaacuagaa
auaacuuugcaaggagagccaaagcuaagacccccgaaaccagacgagcu
accuaagaacagcuaaaagagcacacccgucuauguagcaaaauaguggg
aagauuuauagguagaggcgacaaaccuaccgagccuggugauagcuggu
uguccaagauagaaucuuaguucaacuuuaaauuugcccacagaacccuc
uaaauccccuuguaaauuuaacuguuaguccaaagaggaacagcucuuug
gacacuaggaaaaaaccuuguagagagaguaaaaaauuuaacacccauag
uaggccuaaaagcagccaccaauuaagaaagcguucaagcucaacacaaa
aaaucccaaacauauaacugaacuccucacacccaauuggaccaaucuau
cacccuauagaagaacuaauguuaguauaaguaacaugaaaacauucucc
uccgcauaagccugcgucagauuaaaacacugaacugacaauuaacagcc
caauaucuacaaucaaccaacaagucauuauuacccucacugucaaccca
acacaggcaugcucauaaggaaagguuaaaaaaaguaaaaggaacucggc
aaaucuuaccccgccuguuuaccaaaaacaucaccucuagcaucaccagu
auuagaggcaccgccugcuggcuccacgaggguucagcugucucuuacuu
uuaaccagugaaauugaccugcccgugaagaggcgggcauaacacagcaa
gacgagaagacccuauggagcuuuaauuuauuaaugcaaacagaaaccug
cauuaaaaauuucgguuggggcgaccucggagcagaacccaaccuccgag
caguacaugcuaagacuucaccagucaaagcgaacacucaauugauccaa
uaacuugaccaacggaacaaguuacccuagggaagcgcaauccuauucua
gaguccauaucaacaauaggguuuacgaccucguuggaucaggacauccc
gauggugcagccgcuauuaaagguucguuuguucaacgauuaaaguccua
cgugaucugaguucagaccggaguaauccaggucgguuucuaucuacuuu
caaauuccucccuguacgaaaggacaagagaaauaaggccuacuucacaa
agcgccuucccccguaaaugauaucaucucaacuuaguauacccacccca
cccaagaacaggguuuuuuuuuuuuuuuuuuuuuuuuuuuuuuuu
<<<.......<<<<....................................
.<......>...............<<.....>>.............>>.>
>.............<<....>>......................>>>...
........<<<.......>>>...<.<........>.>.<<<<<<.....
....<<<.<<..<<....>>...>>.>>>...<<.<...<<<<.<.....
<<<<<.<<<..<<<.....>>>...<<<..<<<<........>>>>.>>>
....>>>.>>>>>...<<.......>>......>.>>>>......>.>>.
.<<<<<<....<<<<....>>>><<<.<<<<<<<<<<.....<<......
....>>.....>>>>>>>>>>..>>>.<<<<<<<<<<......>>>>>>>
>>>...<<<......>>>....<<<.<<<...<..............<..
..<<<.........>>>....>.......<<<......>>>.........
..................>...>>>>>>........>>>>>>...<<<<<
......>>>>>.........>>>>>><......<<..<<<....>>><<<
<..<<<<........<<<<<..............>>>>>......<<<..
.<<<<.......................>>>>.......>>>.....<<.
.....>>.>>>>.....>>>>..<<<<...<<<<<<<<.<<.........
.......<<<<<<..<<<.........>>>...<<<<<<...........
..>>>>>>....<<<....>>>....>>.>>>>........>>.>>>>>>
>>>>>>.>>.....>.....<<<<<........>>>>>.......<<..<
<<.<<<....<<<<<.<<<<<<..<<<<<.<<<<<<<<..........>>
>>>>>>>>>>>..<<<<((((.>>>><<<<<<...........>>>>>>.
.<<.....<<<..<<<<.....>>>>..>>>.....>>.........<<<
....>>>............>>>>..>>>>>>>......<<<<<<<<<...
<<.......>>...>>>>>>>>>.....)))).<<<<<..<<<<<..<<.
<<<<<<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>.
.....>>>>>.....<<<<<<<....>>>.>>>>...>>>..>>>.>>..
.<.<<<.<<<.................>>>.>>><<<<<...<<<....>
>>.>>>>>......<<<................>>>...>.........<
<<<.......>>>>...............................
Receptor-Ligand Complex Structure
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PDB7ods Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
K31 K61 R63 K67 R73 Y96 G100 H101 R111 P130 I131 T132 R133 K134 Q178 H181 K182 L183 P184 R227 V229 L230 S231 K244
Binding residue
(residue number reindexed from 1)
K2 K32 R34 K38 R44 Y67 G71 H72 R82 P101 I102 T103 R104 K105 Q136 H139 K140 L141 P142 R185 V187 L188 S189 K202
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ods, PDBe:7ods, PDBj:7ods
PDBsum7ods
PubMed34135320
UniProtQ9NX20|RM16_HUMAN Large ribosomal subunit protein uL16m (Gene Name=MRPL16)

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