Structure of PDB 6yef Chain N Binding Site BS01

Receptor Information
>6yef Chain N (length=122) Species: 93061 (Staphylococcus aureus subsp. aureus NCTC 8325) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVKNATPGG
VVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFG
PVARELREGNFMKIVSLAPEVL
Ligand information
>6yef Chain a (length=1545) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaauac
augcaagucgagcgaacggacgagaagcuugcuucucugauguuagcggc
ggacgggugaguaacacguggauaaccuaccuauaagacugggauaacuu
cgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaaa
agugaaagacggucuugcugucacuuauagauggauccgcgcugcauuag
cuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccug
agagggugaucggccacacuggaacugagacacgguccagacuccuacgg
gaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagcaa
cgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuaggg
aagaacauauguguaaguaacugugcacaucuugacgguaccuaaucaga
aagccacggcuaacuacgugccagcagccgcgguaauacguagguggcaa
gcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaag
ucugaugugaaagcccacggcucaaccguggagggucauuggaaacugga
aaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaau
gcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucugu
aacugacgcugaugugcgaaagcguggggaucaaacaggauuagauaccc
ugguaguccacgccguaaacgaugagugcuaaguguuaggggguuuccgc
cccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacgac
cgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugga
gcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugaca
uccuuugacaacucuagagauagagccuuccccuucgggggacaaaguga
cagguggugcaugguugucgucagcucgugucgugagauguuggguuaag
ucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguugggc
acucuaaguugacugccggugacaaaccggaggaagguggggaugacguc
aaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggaca
auacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguuguu
cucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgcu
aguaaucguagaucagcaugcuacggugaauacguucccgggucuuguac
acaccgcccgucacaccacgagaguuuguaacacccgaagccgguggagu
aaccuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaag
ucguaacaagguagccguaucggaaggugcggcuggaucaccucc
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<.<<<<....<<..........>>....>>>>.>>>>>
......<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<<
<<<....>>>>>>......>>>>......<<<<<<<<<....>>>>>>>>
>......<<<<<<...>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<
<<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<.
...>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<<..>>
>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>.
>>>>>>..<<<<.......<<<....>>>......>>>>....<<<<<<.
........................................>>>>>>....
..<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>..
>>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<<
<<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>>
>>>>...<<<<<<<<...<<<<<<<....<<<<<<<<.<.<<<......>
>>.....>>>>>>>>>...........<<....>>.>>>>>>>..>>>>>
.>>>...>>>..>>>>>....<<<<<<<...<...<<<<.<.....>.>>
>>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<<<....>>
>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<<
<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<.<<<<<<..<
<<<<<<<<<......<<........>>..........<<<<<<<......
<.<<<......<<<<<....>>>>>.....<<<<..>>>>...>>.>.>.
.<<<.<<<..<<<<<<.......<<<<<<<<<....>>>..<<<<.....
.>>>>..>>>>>>.....<<<<.<<<<<<<..<<..<<<......>>>>>
...>>>>>>>.....<<<<<.....>>>>>........>>>>........
.>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<
<<.....<<<..<<...<<<....>>>...>>....>>>.....>>>>>>
>......<....<<<<<<<........>>>>>>>....>.....>>>>>>
....<<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>
>.......<<.<.<<<<.<<<..<<<<<<..<<<<....<.<<<<..<<<
..<<<...>>>.>>>.>>>>.>...>>>>..>>>>>>..>>>.>>>>..>
.>>.........<<<<<<<<<....>>>>>>>>>...........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yef Cryo-EM structure of the ribosome functional complex of the human pathogen Staphylococcus aureus at 3.2 angstrom resolution.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		P48 R97 E120
Binding residue
(residue number reindexed from 1)		P48 R97 E120
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6yef, PDBe:6yef, PDBj:6yef
PDBsum6yef
PubMed32852796
UniProtQ2FW16|RL14_STAA8 Large ribosomal subunit protein uL14 (Gene Name=rplN)

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