Structure of PDB 6uri Chain N Binding Site BS01
Receptor Information
>6uri Chain N (length=164) Species:
11676
(Human immunodeficiency virus 1) [
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SRDLEKHNTAANNAACAWLEAQEEEEVGFPVTPQVPLRPMTYKAAVDLSH
FLKEKGGLEGLIHSQRRQDILDLWIYHTQGYFPDWQNYTPGPGVRYPLTF
GWCYKLVPVEPDKVEEANKGENTSLLHPVSLHGMDDPEREVLEWRFDSRL
AFHHVARELHPEYF
Ligand information
>6uri Chain D (length=14) Species:
9606
(Homo sapiens) [
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RMSQIKRLLSEKKT
Receptor-Ligand Complex Structure
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PDB
6uri
Structural basis of CD4 downregulation by HIV-1 Nef.
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
S34 R35 D36 L37 H40 N47 N51 L76 P78 M79 Y81 F121 D123 W124 N126 F139
Binding residue
(residue number reindexed from 1)
S1 R2 D3 L4 H7 N8 N12 L37 P39 M40 Y42 F82 D84 W85 N87 F100
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005525
GTP binding
View graph for
Molecular Function
External links
PDB
RCSB:6uri
,
PDBe:6uri
,
PDBj:6uri
PDBsum
6uri
PubMed
32719457
UniProt
P03406
|NEF_HV1BR Protein Nef (Gene Name=nef)
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