Structure of PDB 6t9l Chain N Binding Site BS01

Receptor Information
>6t9l Chain N (length=82) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKPKVIEEYSPSNDSWKSLMSSAKDTPLQYDHMNRESLKKYFNPNAQLIE
DPLDKPIQYRVCEKCGKPLALTAIVDHLENHC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6t9l Chain N Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6t9l Structure of the transcription coactivator SAGA.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		C78 H93 C98
Binding residue
(residue number reindexed from 1)		C62 H77 C82
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0008047 enzyme activator activity
GO:0008270 zinc ion binding
Biological Process
GO:0006325 chromatin organization
GO:0006338 chromatin remodeling
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006406 mRNA export from nucleus
GO:0045899 positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO:0046822 regulation of nucleocytoplasmic transport
GO:0065003 protein-containing complex assembly
GO:1904802 RITS complex assembly
GO:1905634 regulation of protein localization to chromatin
Cellular Component
GO:0000124 SAGA complex
GO:0005634 nucleus
GO:0005829 cytosol
GO:0046695 SLIK (SAGA-like) complex
GO:0071819 DUBm complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6t9l, PDBe:6t9l, PDBj:6t9l
PDBsum6t9l
PubMed31969703
UniProtP53165|SGF73_YEAST SAGA-associated factor 73 (Gene Name=SGF73)

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