Structure of PDB 6sw9 Chain N Binding Site BS01

Receptor Information
>6sw9 Chain N (length=146) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGKKAPNGEFAGRKLKLKRKKFRWSDIRYKRRVLRLKEKSDPLEGAPQAR
GIVLEKIAVEAKQPNSGMRKAVRVQLIKNGKVVTAFCPGDGAIKFIDEHD
EVIIEGIGGPKGGSMGDIPGIRYKVVKVNRVSLKELVKGRKEKPRR
Ligand information
>6sw9 Chain 2 (length=1497) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggaggccacugcuauggggguccgacuaagcc
augcgagucaagggggcgucccuucugggacgccaccggcggacggcuca
guaacacgucgguaaccuacccucgggagggggauaaccccgggaaacug
gggcuaaucccccauaggccugggguacuggaagguccccaggccgaaag
ggagccguaaggcuccgcccgaggaugggccggcggccgauuagguaguu
ggugggguaacggcccaccaagccgaagaucgguacgggccgugagagcg
ggagcccggagauggacacugagacacggguccaggcccuacggggcgca
gcaggcgcgaaaccuccgcaaugcgggaaaccgcgacggggggaccccca
gugccgugccucuggcacggcuuuuccggaguguaaaaagcuccgggaau
aagggcugggcaaggccgguggcagccgccgcgguaauaccggcggcccg
agugguggccacuauuauugggccuaaagcggccguagccgggcccguaa
gucccuggcgaaaucccacggcucaaccguggggcucgcuggggauacug
cgggccuugggaccgggagaggccggggguacccccgggguaggggugaa
auccuauaaucccggggggaccgccaguggcgaaggcgcccggcuggaac
ggguccgacggugagggccgaaggccaggggagcgaaccggauuagauac
ccggguaguccuggcuguaaaggaugcgggcuaggugucgggcgagcuuc
gagcucgcccggugccguagggaagccguuaagcccgccgccuggggagu
acggccgcaaggcugaaacuuaaaggaauuggcgggggagcacuacaagg
gguggagcgugcgguuuaauuggauucaacgccgggaaccucaccggggg
cgacggcaggaugaaggccaggcugaaggucuugccggacgcgccgagag
gaggugcauggccgccgucagcucguaccgugaggcguccacuuaagugu
gguaacgagcgagacccgcgcccccaguugccagucccucccgcucggga
gggaggcacucuggggggacugccggcgauaagccggaggaaggggcggg
cgacgguaggucaguaugccccgaaacccccgggcuacacgcgcgcuaca
augggcgggacaaugggugccgaccccgaaagggggagguaauccccuaa
acccgcccucaguucggaucgcgggcugcaacucgcccgcgugaagcugg
aaucccuaguacccgcgcgucaucaucgcgcggcgaauacgucccugcuc
cuugcacacaccgcccgucacuccacccgagcggggccuaggugaggccc
gaucuccuucgggaggucgggucgagccuaggcuccgugaggggggagaa
gucguaacaagguagccguaggggaaccuacggcucgaucaccuccu
...<<<<<.[.((((>>>>>.<<<<<<<<<..<<<<<<.<<......<<<
.<<<..<<<..<<.<<<<<<<<....>>>>>>>>.>>>>>......<<..
......<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<<....>>>
>>>.....>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>.....
<<<<<<....>>>>>>.>>>>>>>..>>>>>>>>>.<<<....<<<...<
<<<<<.........>>>>>>.>>>......>>>..<<<<<<<<....>>>
>...>>>>.>>.<<<<<............>>>>>.<<<<<..>>>>>...
>>>>>>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>
..<<<<<<<<...>>>>>>>>...<<<<<<<<.......>>>>>>>>...
..<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>.
.>>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<
<<<<<<<<<....<<<<<<<<.....>>>>>>>>...>>>>>>>>..>>>
>>>>>>...<<<<<.<....<<<<<<<.<..<<<<<<<<<..<<<.....
.>>>.....>>>>>>>>>..>........<<....>>.>>>>>>>....>
>>.>>>...>>>...>>>>...<<<<<<<...<<...<<<<.<.....>.
>>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<...
..>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<....
..<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.<<<
<<<..<<<<<<<<<<......<<........>>..........<<<<<<<
...<<<<........<<<.<<<.......>>>.>>>......>>>>...<
<.<<<..<<<<<<<<.....<<<<<<.<<....>>...<<<<......>>
>>..>>>>>>....<<<<<.<<<<<<<..<<<..<<<<<<<<....>>>>
>>>>>>>...>>>>>>>.....<<<<<.....>>>>>........>>>>>
.....>>.>>>...>>>>>>>>....>>>>>>>...>>.>>>>>>>>...
..<<<<<<<.....<<<..<...<<<<....>>>>...>....>>>....
.>>>>>>>......<....<<<<<<<........>>>>>>>....>....
.>>>>>>.....<<<<<<<.......>>>>>>>.......>>...>>>>>
>>>>>.>>.......<<.<.<<<<.<<...<...<<<<<<<<<..<<<<<
<<<<<<<....>>>>>>>>>>>>..>>>>>>>>>...>...>.>>>>>..
>.>>..........<<<<<<<<....>>>>>>>>.............
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6sw9 Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		P2 K4 K5 A6 N8 F11 R20 W25 S26 D27 R32 R33 R36 K38 R51 K63 N66 S67 D91 G92 G107 G109 P111 K112 M116 D118 K128 S133
Binding residue
(residue number reindexed from 1)		P1 K3 K4 A5 N7 F10 R19 W24 S25 D26 R31 R32 R35 K37 R50 K62 N65 S66 D90 G91 G106 G108 P110 K111 M115 D117 K127 S132
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6sw9, PDBe:6sw9, PDBj:6sw9
PDBsum6sw9
PubMed32029867
UniProtP61994|RS12_PYRAB Small ribosomal subunit protein uS12 (Gene Name=rps12)

[Back to BioLiP]