Structure of PDB 6awc Chain N Binding Site BS01

Receptor Information

>6awc Chain N (length=116) Species: 562 (Escherichia coli)

RKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFA
AQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITD
VTPIPHNGCRPPKKRR

Ligand information

>6awc Chain A (length=1443)

aauugaagaguuugaucauggcucagauugaacgcuggcggcaggccuaa
cacaugcaagucgaacgguaacaggaagaagcuugcuucuuugcugacga
guggcggacgggugaguaaugucugggaaacugccugauggagggggaua
acuacuggaaacgguagcuaauaccgcauaacgucgcaagaccaaagagg
gggaccuucgggccucuugccaucggaugugcccagaugggauuagcuag
uaggugggguaacggcucaccuaggcgacgaucccuagcuggucugagag
gaugaccagccacacuggaacugagacacgguccagacuccuacgggagg
cagcaguggggaauauugcacaaugggcgcaagccugaugcagccaugcc
gcguguaugaagaaggccuucggguuguaaaguacuuucagcggggagga
agggaguaaaguuaauaccuuugcucauugacguuacccgcagaagaagc
accggcuaacuccgugccagcagccgcgguaauacggagggugcaagcgu
uaaucggaauuacugggcguaaagcgcacgcaggcgguuuguuaagucag
augugaaauccccgggcucaaccugggaacugcaucugauacuggcaagc
uugagucucguagagggggguagaauuccagguguagcggugaaaugcgu
agagaucuggaggaauaccgguggcgaaggcggcccccuggacgaagacu
gacgcucaggugcgaaagcguggggagcaaacaggauuagauacccuggu
aguccacgccguaaacgaugucgacuuggagguugugcccuugaggcgug
gcuuccggagcuaacgcguuaagucgaccgccuggggaguacggccgcaa
gguuaaaacucaaaugaauugacgggggcccgcacaagcgguggagcaug
ugguuuaauucgaugcaacgcgaagaaccuuaccuggucuugacauccac
ggaaguuuucagagaugagaaugugccuucgggaaccgugagacaggugc
ugcauggcugucgucagcucguguugugaaauguuggguuaagucccgca
acgagcgcaacccuuauccuuuguugccagcgguccggccgggaacucaa
aggagacugccagugauaaacuggaggaagguggggaugacgucaaguca
ucauggcccuuacgaccagggcuacacacgugcuacaauggcgcauacaa
agagaagcgaccucgcgagagcaagcggaccucauaaagugcgucguagu
ccggauuggagucugcaacucgacuccaugaagucggaaucgcuaguaau
cguggaucagaaugccacggugaauacguucccgggccuuguacacaccg
uaacaagguaaccguaggggaaccugcgguuggaucaccuccu

.......<<<<<.[.((((>>>>>.<<<<.<<<<<...<<<<<<......
<<<.<<<...<<..<<.<...<<.<<<<<.......>.>>>>..>>.>..
>>>>.......<<.......<<<<<<<..<<...<<<<<<<...<<....
.<<<<<......>>>>>......>>.......<<......>>....<<<<
<<..<<....>>>>>>>>.>>>>>>>..>>.>>>>>>><<<..<.<<<..
.<<<<<<.........>>>>>>.>>>....>.>>>..<<<<<<<<....>
>>...>>>>>.>>.<<<<<............>>>>>.<<<.<..>.>>>.
..>>>>>>.........<<...<<<<<<....>>>>.>>>>...>.>>>>
>...<<<<.......<<<....>>>......>>>>..<<.<<<<<.....
...<<<<<<<<.......>>>>>>>>..........>>>>>....>>.<<
<<<(((...<<<<<........))).........>>>>>>>>>>..>>>>
>>>>>..........<<<((.....<<<<...<<<.<<<<<<<.<<<<<<
<<<<......<<<<<<.....>>>>>>....>>>>>>>>..>>>>>>>>>
...<<<<<<<<...<<<<<<<....<<<<<<<<.<.<<<......>>>..
...>>>>>>>>.>..........<<....>>.>>>>>>>..>>>.>>>>>
...>>>...>>>>....<<<<<<...<<...<<<<.<.....>.>>>>..
.>>>>>>>>..........<<<<<<..<<<<<<.<<<<<.....>>>>>.
>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.......<<<....
>>>.....>>>..)))).].<<<<.<<<<<<<.<<..<<<<...<<<<<<
<<<<......<<........>>..........<<<<<<<......<<<<<
<<..<<<<<<......>>>>>>...<<....>>..>>>>>.>>.<<<.<<
<..<<<<<<.......<<<<<<<<......>>..<<<<......>>>>..
>>>>>>.....<<<<.<<<<<<<...<....<<.....>>..>....>>>
>>>>.....<<<<<.....>>>>>........>>>>.........>>>..
.>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<<....
.<<<..<....<<......>>....>....>>>.....>>>>>>>.....
.<....<<<<<<<........>>>>>>>....>......>>>>.....<<
<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>......
.........<<<<<<<<<....>>>>>>>>>............

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6awc Structure of RNA polymerase bound to ribosomal 30S subunit.
• Resolution: 7.9 Å
• Binding residue (original residue number in PDB): N28 G38 N39 W43 T45 G47 G48 G53 K56 I115 H117 N118 G119 C120 R121 K124 R127
• Binding residue (residue number reindexed from 1): N17 G27 N28 W32 T34 G36 G37 G42 K45 I104 H106 N107 G108 C109 R110 K113 R116

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0005515 protein binding
• GO:0019843 rRNA binding
• GO:0070181 small ribosomal subunit rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6awc, PDBe:6awc, PDBj:6awc
• PDBsum: 6awc
• PubMed: 29027901
• UniProt: P0A7R9|RS11_ECOLI Small ribosomal subunit protein uS11 (Gene Name=rpsK)