Structure of PDB 5xs0 Chain N Binding Site BS01
Receptor Information
>5xs0 Chain N (length=184) Species:
9606
(Homo sapiens) [
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CFGQCQYTAEEYQAIQKALRQRLGPEYISSRMAGGGQKVCYIEGHRVINL
ANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAFVRVQLKDGSYHEDV
GYGVSEGLKSKALSLEKARKEAVTDGLKRALRSFGNALGNCILDKDYLRS
LNKLPRQLPLEVDLTKAKRQDLEPSVEEARYNSC
Ligand information
>5xs0 Chain Y (length=10) [
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cccccccccc
Receptor-Ligand Complex Structure
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PDB
5xs0
Structural Basis of Homology-Directed DNA Repair Mediated by RAD52
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
L132 K133
Binding residue
(residue number reindexed from 1)
L108 K109
Binding affinity
PDBbind-CN
: Kd=5.6nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0000724
double-strand break repair via homologous recombination
GO:0000730
DNA recombinase assembly
GO:0006281
DNA repair
GO:0006310
DNA recombination
GO:0045002
double-strand break repair via single-strand annealing
Cellular Component
GO:0005634
nucleus
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Biological Process
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Cellular Component
External links
PDB
RCSB:5xs0
,
PDBe:5xs0
,
PDBj:5xs0
PDBsum
5xs0
PubMed
30428330
UniProt
P43351
|RAD52_HUMAN DNA repair protein RAD52 homolog (Gene Name=RAD52)
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