Structure of PDB 5tx1 Chain N Binding Site BS01

Receptor Information
>5tx1 Chain N (length=473) Species: 46928 (Human adenovirus 26) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEVPFVPPRYMAPTEGRNSIRYSELAPQYDTTRVYLVDNKSADIASLNYQ
NDHSNFLTTVVQNNDFTPAEASTQTINFDERSRWGGDLKTILHTNMPNVN
EYMFTSKFKARVMVSRKHPEGVVETDLSQDKLEYEWFEFTLPEGNFSETM
TIDLMNNAILENYLQVGRQNGVLESDIGVKFDSRNFKLGWDPVTKLVMPG
VYTYEAFHPDVVLLPGCGVDFTESRLSNLLGIRKKQPFQEGFRIMYEDLE
GGNIPALLDVPKYLESKKKVEDETKNAKKVEVLPIEKDESGRSYNLIQGT
HDTLYRSWYLSYTYGDPEKGVQSWTLLTTPDVTCGAEQVYWSLPDLMQDP
VTFRSTQQVSNYPVVGAELMPFRAKSFYNDLAVYSQLIRSYTSLTHVFNR
FPDNQILCRPPAPTITTVSENVPALTDHGTLPLRSSIRGVQRVTVTDARR
RTCPYVYKALGIVAPRVLSSRTF
Ligand information
>5tx1 Chain O (length=19) Species: 46928 (Human adenovirus 26) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AKRLRVEDDFNPVYPYGYA
Receptor-Ligand Complex Structure
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PDB5tx1 Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
V215 T216 V282 Y285 L286 V292 K324 K325 V326 E327 G345 H347
Binding residue
(residue number reindexed from 1)
V193 T194 V260 Y263 L264 V270 K278 K279 V280 E281 G299 H301
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
GO:0075509 endocytosis involved in viral entry into host cell
Cellular Component
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5tx1, PDBe:5tx1, PDBj:5tx1
PDBsum5tx1
PubMed28508067
UniProtA4ZKL2

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