Structure of PDB 5oql Chain N Binding Site BS01

Receptor Information
>5oql Chain N (length=443) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEKDAEEEELEKFVLGAKETFREQLFRPAWEDSDDERLTISLAGATRLRK
LRISESEDLVSGIEYARRLRQQYLRLYPQPDWAKPLPLDSFLRDANSFKV
KLRPETIDIQRTRDIPDTHKAAISSLAFHPRYPILLSSSTSSIMYLHKLD
ASAYPTPNPLLTSVHVKRTDLRRAAFVGPDGGEIIFAGRRRYFHCWNLSS
GLVKKVSKIQGHQKEQRTMERFRVSPCGRYMALVASDKKGGGMLNIINVG
TMQWIAQARIDGRHGVADFAWWSDGNGLTIAGRDGQVTEWSMITRRTVGI
WRDEGSIGGTVMALGGRNGPAELGGDRWVAIGSNSGILNVYDRNDLIEIR
IKKYPTPTRVFEQLTTSISVVAFSPDGQLLAFGSQHKKDALRLVHLPSCT
VYRNWPTEQTPLGRVTAIAFSSKSDVLAVGNDVGRVRLWEIRG
Ligand information
>5oql Chain 1 (length=1350) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggggggauguccgggucgcccugggcaccucuccgcggcagcgcaagccg
uuucauacgucgccgcaaucgcgaggggcuccaagcggucgccggcgagc
accaccccagccccgcgccgcccccagcgcaccgcgcgcaggggggccgg
cgcggcaucugggaagacuccuaaggcgcaagggaauaccccgugcgccg
gggguugggcucugugggugcuuggccgcuggccagaccuacuucaaagc
caccggggguaccuaccgguugucucggucgggccuccucuuggggcgcc
uaggcggugucuucgggucgcgugcagccucccguccucgccugccgaca
gcgcucuggggaauucaggaggggaaagcagaugugccccgcggcgagac
uggcgccggacgagcugcuggggcacgcggguacgcuagccgcacgauag
uuaccugguugauucuuagucauaugcuugucucaaagccaugcgucuaa
guauaagcaauuacagcgaaacugcgaauggcucauuaaaucaguuaucg
uuuauuugauaguauggauaaccgugguaauucuagagcuaauacaugcg
uauuuauuagggugauucauaauaacuucucgaaucgcacggccuugcgc
cggcgaugguucauucaaauuucugcccuaucaacuuucgacggcugggu
auuggccagccguggugacaacggguaagagaggagccugagaaacggcu
acuacauccaaggaagggcaggcgccaaauuacccaaucccgacacgggg
agguagugacaauaaauacugauacagggcuccgggucuuguaauuggaa
ugaguacaauuuaaaucccuuaacgaggaacaauuggagggcaagucugg
ugccagcagccgcgguaauucccuccaauagcguauauugcucguaguug
aaccugauuaauagggacagucgggggcgucaguauucaauugucagagg
ugaaauucuuggauuuauugaagacuaacaacugcgaaagcauucgccaa
ggauguuuucauuaaucaggaacgauuagggaucggacggcguuuauuuu
ugacccguucggcaccuuacgauaaaucaaaauguuugggaguauggucg
caugacggaagggcaccaccagggguggagccugcgcgcgcgcuacacug
acagagccagcgaguacucccuuggccgagaggcccggguaaacucuguc
gugcugaggaaucccuaguaagcgcaagucaucagcuugcguugauuacg
ucccugcccuuuguacacaccgcccgucgcuacuaccgauagaggaagua
<<.<<<.<<<<<<<<....>>>>>>>>>>>.>.>.<<<<.<..>..>>>>
.........<<<<<<<.<<<<<..<<<<>>>>..>>>>>.>>.>>>>>..
..<..<<<<<..<<<<<<<<<<<<<.<<<<.....>>>>..>>>>>.>>>
>>>>>...>>>>>..>........<<<<<<.<<<.....>>>.>>>>>>.
........................<<<...>>>.................
....<<<<<..<<<<<<<<.....>>>>>.>>>>>>>>.....<<<<<<.
..<<<<<<<....<<<<..<<.....>>..>>>>....>>>>.>>>....
>>>>>>...........................<<<<.<<<<<<<..<.<
<<<..>>>>.>..>>>>>.>>.>>>><<<<.<.....>.>>>>.......
..................<..<<<<<<...<.<<..<<<<.<<<<<....
<<....<<.......>>...>>.>>......<<<.......<<<..<<..
<<....<<<.......<.<..<..<<<.....>>>..>.....>>....<
...<<<<<<.<......>.>>>>>>.....>...<<<<.<<<<.....>>
>>>>>>....>>>...>>>>..>>>.<<<....<<<....<<<<<<<<..
.....>>>>>>>>>>>......>>>...>>><<.<<<..........>>>
.>>.<.<<<..>>>.>.>>>>>>........<<<...<<<<<...>>>>.
>>>>..>>...>.>....<<<<<<<<<<<<<...>>>>>>>>.>>>>>..
...<<..<...........>..>>.........<<<<<<.......<<<.
...>>>................>>>>>>..>>>>>>.>.<.<<...<<<.
<<.....>>.....<<<<<.<<...<<<<..<<<.<<<<<<.....<<<.
.....>>>........>>>>>>.>>>.......<<....>>...>>>>..
>>.>>>.>>....>>>...>>.>..<..<<..<<<<<<<<.<<<......
.>>>>>>>>>>>..>>.....<....>....>..................
..<<<<<<<<<<<<<..<<.<<<<<<..<<<.<<<..>>>.>>>.....<
<<<<<<..............<<.<<<<....>>>>.>>.....>>>>>>>
..........>>>>>>....<<<<<<<<.......>>>>>>>>......>
>...>>>>>>>............>>>>>>.<<<<.<<......>>.>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5oql 3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
T152 R153 R155 K156 Q178 I263 Q264 R322 R343 R344 R345 Y346 K359 S361 K362 Q367 R371 T372 R375 K392 K393 R417 H418 R437 N488 S542 Q560 H561 K563 D564 N579 T582 E583 Q584 T585 P586 R589
Binding residue
(residue number reindexed from 1)
T46 R47 R49 K50 Q72 I109 Q110 R168 R189 R190 R191 Y192 K205 S207 K208 Q213 R217 T218 R221 K238 K239 R263 H264 R283 N334 S367 Q385 H386 K388 D389 N404 T407 E408 Q409 T410 P411 R414
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006364 rRNA processing
Cellular Component
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0034388 Pwp2p-containing subcomplex of 90S preribosome

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5oql, PDBe:5oql, PDBj:5oql
PDBsum5oql
PubMed28967883
UniProtG0SBN9

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