Structure of PDB 5jbh Chain N Binding Site BS01

Receptor Information
>5jbh Chain N (length=145) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKKAPNGEFAGRKLKLKRKKFRWSDIRYKRRVLRLKEKSDPLEGAPQARG
IVLEKIAVEAKQPNSGMRKAVRVQLIKNGKVVTAFCPGDGAIKFIDEHDE
VIIEGIGGPKGGSMGDIPGIRYKVVKVNRVSLKELVKGRKEKPRR
Ligand information
>5jbh Chain 2 (length=1495) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggaggccacugcuauggggguccgacuaagcc
augcgagucaagggggcgucccuucugggacgccaccggcggacggcuca
guaacacgucgguaaccuacccucgggagggggauaaccccgggaaacug
gggcuaaucccccauaggccugggguacuggaagguccccaggccgaaag
ggagccguaaggcccgcccgaggaugcggcggcggccgauuagguaguug
gugggguaacggcccaccaagccgaagaucgguacgggccgugagagcgg
gagcccggagauggacacugagacacggguccaggcccuacggggcgcag
caggcgcgaaaccuccgcaaugcgggaaaccgcgacggggggacccccag
ugccgugccucuggcacggcuuuuccggaguguaaaaagcuccgggaaua
agggcugggcaaggccgguggcagccgccgcgguaauaccggcggcccga
gugguggccacuauuauugggccuaaagcggccguagccgggcccguaag
ucccuggcgaaaucccacggcucaaccguggggcucgcuggggauacugc
gggccuugggaccgggagaggccggggguacccccgggguaggggugaaa
uccuauaaucccggggggaccgccaguggcgaaggcgcccggcuggaacg
gguccgacggugagcgcggaaggccaggggagcgaaccggauuagauacc
cggguaguccuggcuguaaaggaugcgggcuaggugucgggcgagcuucg
agcucgcccggugccguagggaagccguuaagcccgccgccuggggagua
cggccgcaaggcugaaacuuaaaggaauuggcgggggagcacuacaaggg
guggagcgugcgguuuaauuggauucaacgccgggaaccucaccgggggc
gacggcaggaugaaggccaggcugaaggucuugccggacgcgccgagagg
aggugcauggccgccgucagcucguaccgugaggcguccacuuaagugug
guaacgagcgagacccgcgcccccaguugccagucccucccgcucgggag
gaggcacucuggggggacugccggcgauaagccggaggaaggggcgggcg
acgguaggucaguaugccccgaaacccccgggcuacacgcgcgcuacaau
gggcgggacaaugggacccgaccucgaaaggggaagggaauccccuaaac
ccgcccucaguucggaucgcgggcugcaacucgcccgcgugaagcuggaa
ucccuaguacccgcgugucaucaucgcgcggcgaauacgucccugcuccu
ugcacacaccgcccgucacuccacccgagcggaguccgggugaggccuga
ucuccuucgggaggucaggucgagcccgggcuccgugaggggggagaagu
cguaacaagguaaccguaggggaaccuacggcucgaucaccuccu
...<<<<..[.((((.>>>>.<<<<<<<<<....<<<<.<<......<<<
.<<<..<<<..<<.<<<<<<<<....>>>>>>>>.>>>>>......<<..
......<<<<<.<...<...<<<<<<<.<<<<<....<<<<<......>>
>>>.....>>>>>...<<<<<<<<<.<<<....>>>>>>>>>>>>....<
<..<<<....>>>>>.>>>>>>>..>.>.>>>>>.<<<....<<<..<<<
<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>
...>>>>.>>.<<<<<............>>>>>.<<<<....>>>>...>
>>>>>.........<<<....<<<<....>>>>..>>>..>>..>>>>..
.<<<<<<<<...>>>>>>>>...<<<<<<<.........>>>>>>>....
.<<<<<((.....<<<<<.....<<..))>>.......>>>>>>>>>>..
>>>>>>>>>..........<<<((......<<....<<<.<<<<<<<.<<
<<<<<<<.....<<<<<<<<.....>>>>>>>>....>>>>>>>..>>>>
>>>>>...<<<<<<.....<<<<<<<<<<.<<<<<<<<<..<<<......
>>>.....>>>>>>>>>.>>>.......<<....>>.>>>>>>>....>>
>.>>>...>>>....>>....<<<<<<<...<<...<<<<.........>
>>>...>>>>>>>>>.........<<<<<<..<<<<<<<<<<<<<<....
.>>>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<.....
.<<<<....>>>>....>>>..)))).]<<<<<.<<<<<<<..<<.<<<<
<<..<<<<<<<<<<......<<........>>..........<<<<<<<.
..<<<<........<<<.<<<<.....>>>>.>>>......>>>>...<<
.<<<..<<<<<<<<<....<<<<<<.<<....>>...<<<<......>>>
>..>>>>>>....<<<<<.<<<<<<<...<...<.<<<<<<<..>>>>>>
>>>.....>>>>>>>.....<<<<<.....>>>>>........>>>>>..
..>>>.>>>...>>>>>>>>....>>>>>>>...>>.>>>>>>>>.....
<<<<<<<.....<<<..<<..<<<<....>>>>..>>....>>>.....>
>>>>>>......<....<<<<<<<........>>>>>>>....>.....>
>>>>>.....<<<<<<.........>>>>>>.......>>...>>>>>>>
>>>.>>....<..<<.<.<<<<.<<<..<<<<<<<<<<<<<..<<<<<<<
<<<<<<..>>>>>>>>>>>>>..>>>>>>>>>>>>>..>>>.>>>>..>.
>>...>.......<<<<<<<....>>>>>>>..............
Receptor-Ligand Complex Structure
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PDB5jbh Cryo-EM study of start codon selection during archaeal translation initiation.
Resolution5.34 Å
Binding residue
(original residue number in PDB)
G3 K5 P7 N8 G9 E10 R14 R20 K21 F23 R24 S26 Y30 K31 R32 R33 R36 P48 Q49 A50 R51 V60 E61 Q64 P65 G68 M69 I78 K79 G90 D91 E106 G107 I108 G109 G110 P111 D118 P120 G121 R123 R131 S133 K135 K142
Binding residue
(residue number reindexed from 1)
G1 K3 P5 N6 G7 E8 R12 R18 K19 F21 R22 S24 Y28 K29 R30 R31 R34 P46 Q47 A48 R49 V58 E59 Q62 P63 G66 M67 I76 K77 G88 D89 E104 G105 I106 G107 G108 P109 D116 P118 G119 R121 R129 S131 K133 K140
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5jbh, PDBe:5jbh, PDBj:5jbh
PDBsum5jbh
PubMed27819266
UniProtP61994|RS12_PYRAB Small ribosomal subunit protein uS12 (Gene Name=rps12)

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