Structure of PDB 7qvp Chain Ml Binding Site BS01
Receptor Information
>7qvp Chain Ml (length=50) Species:
9606
(Homo sapiens) [
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SSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL
Ligand information
>7qvp Chain L1 (length=156) [
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cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<....>><<<<<<<<<.....>>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB
7qvp
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
F7 K15 K18 Q19 I23 W26 I27 M29 K30 T31
Binding residue
(residue number reindexed from 1)
F6 K14 K17 Q18 I22 W25 I26 M28 K29 T30
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
Biological Process
GO:0006412
translation
Cellular Component
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Cellular Component
External links
PDB
RCSB:7qvp
,
PDBe:7qvp
,
PDBj:7qvp
PDBsum
7qvp
PubMed
36302773
UniProt
A0A7N4PFJ2
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