Structure of PDB 7qep Chain M5 Binding Site BS01

Receptor Information
>7qep Chain M5 (length=203) Species: 284813 (Encephalitozoon cuniculi GB-M1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAVNYLREIHRRKQSDVMRYLLRIRVCEYRQRGECFRVEKPTFLERARTL
GYKAKQGYVLYIARVKKGNMKRNYHNGNTRGKCVNAGINQIKPSLRKQAS
AEMIAGKKCSNLGVLNSYWVGQDAAYKYYEVIMVDRDHQAIRNDPKINWI
CKGTMKHRECRGLTSASRKSRGLGKGVKFNKSKGGSIRSCWRRRNTLVLQ
KYR
Ligand information
>7qep Chain 1 (length=2319) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucucuguucacgggauugauuggcauuagcggcgaugaaggacgugcagg
aggacgauaugcguuguuguugugacggugucugaauugugugcggugug
cacggggaccccuuggacuuaagcauaucaguaaagggaggagaagaaac
caaaugggauugccugaguagcggcgagugaaauggcaugagccugugug
guaacugcguggcggguuguguuuguggcagcagcggcgagugcgauuga
auucggaugcggagagggcgaugugccuguaggcgcggcggcuuuuuuug
ugaguaguguugcuugguagugcagcgcgaaugcggugguggaugcaccg
aaggcuaaauauggcugaugaccgauagcggauaaguagagugauugaag
ugugaaaaggaggaugaugagaaaugaaagugaauggagugaauggggga
uguucccgcccgucuugaaacacggaccaaggagacgacggcaggauugu
uuuccgagaggggaggaugcugcggucggacccgaaagauggugagcuau
guguguguugauugaagggaugcgaaaguguucuggaggaucuaagccgu
ucugacgugcaacucgauggcaugacaugugcauaggggcgaaagaccaa
acgaaccaucugguagcugguucccucugaaaugucucucaggacagcgg
cgacggguguaagauguuguaaagcacuaaugcgcugcguuaaacuuuga
agaugucuuuuaaguuguugccagugggcauacugugguaagcauggugu
gcgagaagggaugaaccuuuaagcgggcuaaggagucuuaugcaagguga
auccggcggccugauuuugacagccgaauugggcggcggagaaaauggaa
gggauugaauugcauuccgaugccugcgggggaguaucugaguaaggggg
cgguaucguucugcugaagguccugcgugagcggggguggaggggcgaua
ugugcagaucuugguagcaguaacaaggaaaugauuugcgcuggacgagg
guucccuguggcaggggugaaucgacuguggauacggaggugcauugaua
guuguguguauugcggcugggaggcgacuuggcugugacggaugggggcg
gcccuguccaggauagcagaacuggaugucugcugcggauuguuaugaug
cgaagcagcgaugggcgagccuguuccgaugaaaaagaggcugcuuuguc
guaccuagaccgcaucugguguccacuguuugccgcggaaguguuuugug
caagggccguaagggaagucggcaagauugauguguaacuucgggagaag
gauuggcucuagcgugcuagaacuguuuguuguggggaaucugacuguuu
acuaaaaacauagcuuuguguguggacgcaaagugaauucugcccagugc
acuuuuaguuacggccuguugggcuaagcgaguguaaacggcgggaguaa
cuaugacucucuuaagguagccaaaugccucgucauguaauuagugacgc
gcaugaauggagcaacgagauucccacugucccuacggccugucuuguga
accuacagccaagggaacgggcuugggcugaucagcggggaaagaagacc
cuguugagcuugacucuagcaugugugaagugcugggugcccagugcuuu
guggauggauguggggaguuuggcuggggcggcacgacugcuaaagacua
acgcagacguccuaaggcgggcucagcggggaaggaaaccacgcguggag
cacaagggcacaagccugcuugagacuguuccuauugcgggacuguuugg
gggaaacccuggccuagagaucccauguccuauugugcgugggacauggg
ugacagaaaaguuaccacagggauaacuggcuuguagcagccgagcgacc
auagcgacgcugcuuuuugauucuucgaugucggcucuuccuaucaucgc
gaagcagagauugcgaaguguuggauuguucacccaccaacagggaacgu
gagcuggguuuagaccgucgugagacagguuaguuuuacccuacugugug
gacugugcagcagaucuugauaguacgagaggaacucuugauugcgaccu
cugguggagcggcgugccugcuggcugcugcggagcuacgucgggaguau
aauggcugaaggccucuaagccugaagaccgacugcgcgguguguguggc
ggaagacgaccgcugugugugcaagcugugcggauggaggaggauuccga
cauuuugaggcugugcauu
[<<<<<<<<<<.......[..<<<<<<<<<..<......<<<<<<.....
...>>>.....<<<<<......>>>>>...>>>.....<<<<<<...>>>
>>>>....<<<<<<.....<......>......>>>>>.>.........<
<....>>...<<<<......<<.....>>.....>>>>...<<<......
....<<<<...>>>>...........<<<.<<.<<<.<.....<<<....
..>>>..((......<<<.....))>>>...>.>>>.>>.>>>.......
......<<<<<<<........>>>>>>>.....<<<<<..<.<<<>>>>>
..>>>........>>>>>>>.>>...............<<....>>....
]............................>>>>>>>>>>....<<<<...
....>>>>.<<<<........>>>><<<<<<....<<<<.<<<<.<<<..
...<<....>>....>>>.>>>>.>>>>..<<.<...<<<<<<.....<<
<<<<<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<..
<<.<<........>>>>.>>>....>>>>>>>>>...<<.......>>..
....>>>>>>......>.>>..<<<<<<....<<<<<....>>>>><<<<
<<<<<....<<<<<<<<<...<<<...<<<<<<<.>>>>>>>..>.>>..
.>>>>>>>..>>...>>>>>>>.>>..<<<<<<<<<<.....>>>>>>>>
>>...<<<<......>>>>...<<<<<<...<<<.(....<<<<<.....
.<<<<...<<<<<<<............>>>>>>>..>>>>..........
.).......>>>>>.>>>...>>>>>>..<<<....>>>.....>>>>>>
<.<<<<<<<<<<......<.<<<<<<....>>>>>>.>...>>>>>>>>>
>..>.....>>>>>><<.....<<<<.<<<....>>><<<.<<<<<<.<<
...<<<<<<.>>>>>>....((<<<<<<......>>....<<<<......
..>>>>.))...<<<<<...<<<....>>>.........<<<<<<<....
<<<<<<<<<<<...((((...>>>>>>><.<<<<<<...<<.....>>..
....>>>>>>>.>>>>...>>>>>>>.............>>>>>...>>>
>..>>....<<......>>>>>>>><<<<.....>>>>...>>>......
...<<<<<<<<.<<.........<.....<<<.<....<<..>>.....>
.>>><<.<<<<<<..>>>>>>.>>..........<<<<<<<<<..<<<..
.......>>>..<<<<<<<........>>>>>>>...<<..<<<..<<<<
<<<<...<<<..<<<<<...>>>>>.>>>>>>>>>..>>>>><<<<<<..
.....>>>>>>........<...........<<<<<.......>>>>>..
...>.....>>....>>.>>>>>>>..>..>>.>>>>>>>>...>>>>..
..>>....<<<<<........>>>>>....].<<<..<<<.<<......<
<<<.<<<<<<..<<<<<.<<<<.<<..<<<<<<<<<<..>>>>>>>>>>.
.....>>.>>>>..>>>>>...<<<.....>>>..<.<<<<.........
..>>>>.>..<<...<<<<<<<...<<<.<<.......>>.>>>.....<
<...(((>>....>>>>>>>...<<<.<<<<<......>>>>>.>>>..<
<<....>>>.>>))).......<<<<<<<<<..>>>.>..>>>>>>>>>.
.........>>>>..>>>>>>.......<<.<.<.<<<<<<...<<....
...>>...>>>>>>...>>..>>.......<<<<<.<<<<<<..<<<<<<
<<........>>>>>..>>>.<<<.........>>>.....>>>>>..>.
..>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>.>>>....
.<<<<<<<<<..<<<<..<<...............>>..>>>>.<<<<..
..<<<...<<<<<<.<<.)))).>>>>>>>>...>>>..>>>>...<<.<
...<<<<...........>>>>....>>>...>>>>>>>>>......<<<
<<.......>>>>>....<<<<<<<<<.....<<<<..<<<....>>>..
>>>>....>>>>.>>>>>.
Receptor-Ligand Complex Structure
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PDB7qep Adaptation to genome decay in the structure of the smallest eukaryotic ribosome
Resolution2.7 Å
Binding residue
(original residue number in PDB)
V4 N5 R12 K14 R31 R38 L45 R47 R49 T50 A55 K56 Y62 K67 K68 G69 N70 R73 N79 R81 G82 K83 V85 N90 Q91 K93 P94 S95 R97 K109 S111 N112 K128 D136 D138 N144 D145 K147 W150 G154 K157 H158 R162 S166 S171 R172 K176 G177 V178 K179 N181 K182 G185 R189 W192 R194 R195 R204
Binding residue
(residue number reindexed from 1)
V3 N4 R11 K13 R30 R37 L44 R46 R48 T49 A54 K55 Y61 K66 K67 G68 N69 R72 N78 R80 G81 K82 V84 N89 Q90 K92 P93 S94 R96 K108 S110 N111 K127 D135 D137 N143 D144 K146 W149 G153 K156 H157 R161 S165 S170 R171 K175 G176 V177 K178 N180 K181 G184 R188 W191 R193 R194 R203
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7qep, PDBe:7qep, PDBj:7qep
PDBsum7qep
PubMed
UniProtQ8SQU2

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