Structure of PDB 8uua Chain M Binding Site BS01

Receptor Information
>8uua Chain M (length=122) Species: 1642 (Listeria innocua) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIQQESRMKVADNSGAREVLTIKVLGGSGRKTANIGDVVVCTVKQATPGG
VVKKGEVVKAVIVRTKSGARRQDGSYIKFDENACVIIRDDKSPRGTRIFG
PVARELRENNFMKIVSLAPEVL
Ligand information
>8uua Chain A (length=2894) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuaaguuagaaagggcgcacgguggaugccuuggcacuaggagccgaag
aaggacgggacuaacaccgauaugcuuuggggagcuguacguaagcguug
auccagagauuuccgaaugggggaacccacuaucuuuagucggauaguau
ccuuacgugaauacauagcgugaggaaggcagacccagggaacugaaaca
ucuaaguaccuggaggaagagaaagaaaaaucgauuuccugaguagcggc
gagcgaaacggaaagagcccaaaccaagaagcuugcuucuugggguugua
ggacacucuauacggaguuacaaaagaaaguuauaaaugaagcggucugg
aaaggcccgccaaagacgguaacagcccgguaguugaaauggcuuucccu
ccagaguggauccugaguacgacggaacacgugaaauuccgucggaaucc
gggaggaccaucucccaaggcuaaauacucccuagugaccgauagugaac
caguaccgugagggaaaggugaaaagcaccccggaaggggagugaaacag
uuccugaaaccgugugccuacaaguaguuagagcccguuaaugggugaua
gcgugccuuuuguagaaugaaccggcgaguuacgauuuguugcaagguua
agcggaaaaagcggagccguagcgaaagcgagucugaauagggcgcauaa
guaacaggucguagacccgaaaccaggugaucuacccauguccaggauga
agguaagguaauacuuacuggagguccgaacccacgcacguugaaaagug
cggggaugagguguggguagcggagaaauuccaaucgaacuuggagauag
cugguucucuccgaaauagcuuuagggcuagccucgagguaaagagucau
ggagguagagcacuguuuggacuagcgaauucagauaaacuccgaaugcc
auguacuuauacucgggagucagacugcgagugauaagauccguagucga
aagggaaacagcccagaccaccaguuaagguccccaaauauauguuaagu
ggaaaaggaugugggguugcuuagacaaccaggauguuggcuuagaagca
gccaccauugaaagagugcguaauagcucacuggucgagugaccccgcgc
cgaaaauguaccggggcuaaacauauuaccgaaacuguggaugaaccuag
guucgugguaggagagcguucuaagggcggugaagucagaccggaaggac
ugguggagcgcuuagaagugagaaugccgguaugaguagcgaaagaaggg
ugagaaucccuuccaccgaauaucuaagguuuccugaggaaggcucgucc
gcucaggguuagucgggaccuaagccgaggccgauaggcguaggcgaugg
acaacagguagagauuccuguaccagugcuaauuguuuaaccgauggggu
gacacagaaggauagggaaucgcacgaauggaaaugugcguccaagcagu
gagugugagaaguaggcaaauccgcuucuugcgaagcaugagcugugaug
gggaagcggaaguuccugauuucacgcugucaagaaaagccucuaggaag
aguaguacugcccguaccgcaaaccgacacagguagaugaggagagaauc
cuaaggugagcgagagaacucucguuaaggaacucggcaaaaugaccccg
uaacuucgggagaaggggugcucuauuagggugcaagcccgagagagccg
cagugaauaggcccaggcgacuguuuagcaaaaacacaggucucugcaaa
accguaaggugacguauaggggcugacgccugcccggugcuggaagguua
agaggagugcuuagcuucggcgaagguacgaauugaagccccaguaaacg
gcggccguaacuauaacgguccuaagguagcgaaauuccuugucggguaa
guuccgacccgcacgaaaggcgcaacgaucugggcacugucucaacgaga
gacucggugaaauuauaguaccugugaagaugcagguuacccgcgacagg
acggaaagaccccguggagcuuuacugcaaccugauauggaauguuugua
ccgcuuguacaggauagguaggagccgaagagacgugugcgcuagcauac
gaggaggcaauggugggauacuacccuggcuguaugaccauucuaacccg
ccacgcuaagcgcguggggagacagugucaggugggcaguuugacugggg
cggucgccuccuaaagaguaacggaggcgcccaaagguucccucagaaug
gauggaaaucauucgcagaguguaaaggcacaagggagcuugacugcgag
acugacaagucgagcagggacgaaagucgggcuuagugauccggugguuc
cgcauggaagggccaucgcucaacggauaaaagcuaccccggggauaaca
ggcuuaucucccccaagaguccacaucgacggggagguuuggcaccucga
ugucggcucgucgcauccuggggcuguagucggucccaaggguugggcug
uucgcccauuaaagcggcacgcgagcuggguucagaacgucgugagacag
uucggucccuauccgucgcgggcgcaggaaauuugagaggagcuguccuu
aguacgagaggaccgggauggacacaccgcugguguaccaguuguuccgc
caggagcaucgcuggguagcuauguguggcagggauaaacgcugaaagca
ucuaagcgugaagccccccucaagaugagauuucccauuucuucggaaag
uaagaucccugaaagaugaucagguagauagguuuggaguggaaguguag
cgauacauggagcggacaaauacuaaucgaucgaggacuuaacc
<<<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<....
..<<<<<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>....
.>>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<
<<<<<<<<.........>>>>>>>>>.>>....<<<<<<.....<<....
>>......>>>>>.>.........<<....>>..<<<<<......<<...
..>>.....>>>>>..(((....<<<<<<<<....>>>>>>>>......<
<<<<<<<<<....<<<<........<<<<<<<<<.<<<.....<<<<...
...>>>>.((......<<<.....))>>>...>>>...>>>>>>>>>.>>
>>>>>>>>..>>>>.....<<<<<<<<.........>>>>>>>>......
<<<<<..<<<<>>>>>..)))......]].>>>>>>>.]]..........
.....<<....>>....]].........<<<<....>>>>..........
...}....>>>>>>>>>>>.......<<<<..<<<<......>>>>..>>
>>...<.<........>.>.<<<<<<....<<<<<<<<<<<<<..<<<..
.<<.......>>...>>>...<<....>>..<<<<.....>>>>......
>>>>>>>>>>>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<...
.<<<<<<......>>>>>>.....>>>...<<<.<<<<<........>>>
>>>>>....>>>>>>>>>...<<<.....>>>......>>>>>>......
>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<.....<<<<<<<
<<.....<<<...<<<<<<<<........>>>>>>>>..>>.>.....>>
>>>.>>>>...>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>..
..<<<......>>>...<<<<.<<<...<<<(((.....<<<<<<.....
......<<..<<<<<<<<<<.......<<<<<.<<...<<<<.......>
>>>...>>.........<<......>>...>>>>>...>>>>>>>>>>.>
>...........))).....>>>>>>.>>>...>>>>>>><<<<<<<..>
>>>>>>....>>>>>><.<<<<<<<.<<......<<<<<.<<....>>.>
>>>>...>>.>>>>>>>..>.....>>>>>><......<<....<<<<<<
.......>>>>>><<<<....<<<<<.<<<..<<<<<<...<<.....>>
.>>>>>>....((<<<<.<<...<<<...<<<....>>>...>>>...>>
...<<<<<........>>>>>))<<<<<<<<.<<......<<...<<<<<
...<<<<..<<<..<<<<<.<<<<<...(((....>>>>>.<<..<<<<<
..<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>..>>>>>...>
>...........>>>>>...>>>...>>>>........>>>>>..>>..>
>.>>>>>>>>>>>>.>>>.....<<......>>>>>>>.<<<<.....>>
>>..>>>>..<<<<....<<<<<<<<.<<.........<.....<<<<<.
....<..>......>>>>><<<<<....<<<<....>>>>...>>>>>..
..........<<<<<<<<<..<<<.........>>>..<<<<<<<.....
<<<....>>>.......>>>>>>>..<<<<.<<<..<<<<<<<..<<<<.
.<<...<<<<<<.<<....>>..>>>>>>...>>..>>>>>>>>>..>>>
>><<<<<<.......>>>>>>........<...........<<<<<<...
..>>>>>>.....>....>>>>...>>.>>>>>>>..>..>>.>>>>>>>
>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<<<.((
(.[[......<<<<.[[<<<<..<<<<<.<<<<<<<<<.<<<<<.<<<<<
<.<<<.<.........<<<<<..<<<.......<<<<<<<....>>>>>>
>....>>>............>>>>>>.>>>.>>>>>>.>>>>>....<<.
<<<<<<.....>>>>>>>>.....>>>>>>>>>..>>>>>..<<<<....
.>>>><<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<
<.......>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<
<<<....>>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.(
(..>>>>..))>>>>>>>.............>>>>..]]>>>>.......
<<<<.<.<<<<<<...<<.......>>...>>>>>>...>>>>.>.....
..<<<<<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<..
...>>>>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>
>>>....]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.
..............>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<.)
))>>>>>>..>>>>>...>>>>.>>>>>...<<<.<..<<<<<.......
....>>>>>...>>>>.>>>>.......>>>>>>>..<<<<....>>>>.
...<<<<<<<<<.......>>>>>....<<<<<<<<..<<....<<<<<.
...>>>>>...>>...>>>>>.>>>...>>>>....>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uua Mechanistic insights into the alternative ribosome recycling by HflXr.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
M1 Q4 E5 S6 I22 K23 G29 R30 R70 Y76
Binding residue
(residue number reindexed from 1)
M1 Q4 E5 S6 I22 K23 G29 R30 R70 Y76
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8uua, PDBe:8uua, PDBj:8uua
PDBsum8uua
PubMed38407413
UniProtA0A0U5AP82

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