Structure of PDB 8red Chain M Binding Site BS01

Receptor Information
>8red Chain M (length=329) Species: 571 (Klebsiella oxytoca) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTPSGNGVDQGETTQSLQDYLMWQVELTPFTDTDRAIATSIVDAVDDTGY
LTIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAAKDLRDCLLIQL
SQFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLI
QSLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSSLESANDTLLRV
SRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSP
RGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLT
SMLSEQGIMVARRTVAKYRESLSIPPSNQ
Ligand information
>8red Chain N (length=46) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gctggcacgacttttgcactcgatatcgcatgctgttgcacattca
Receptor-Ligand Complex Structure
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PDB8red Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		V366 L367 S382 R383 S405 R455 N471 Q472
Binding residue
(residue number reindexed from 1)		V223 L224 S239 R240 S262 R312 N328 Q329
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0016987 sigma factor activity

View graph for
Molecular Function
External links
PDB RCSB:8red, PDBe:8red, PDBj:8red
PDBsum8red
PubMed38170755
UniProtP06223|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

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