Structure of PDB 8rec Chain M Binding Site BS01

Receptor Information
>8rec Chain M (length=347) Species: 571 (Klebsiella oxytoca) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAGTPSGNGVDYQDDELPVYQGETTQSLQDYLMWQVELTPFTDTDRAIAT
SIVDAVDDTGYLTIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAA
KDLRDCLLIQLSQFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLK
EEVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSD
SRWLIKSLESANDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVE
MHESTISRVTTQKYLHSPRGIFELKYFFSSHVNTEGGGEASSTAIRALVK
KLIAAENPAKPLSDSKLTSMLSEQGIMVARRTVAKYRESLSIPPSNQ
Ligand information
>8rec Chain N (length=46) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gctggcacgacttttgcactcgaatatctcatgctgttgcacattc
Receptor-Ligand Complex Structure
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PDB8rec Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		L367 S382 R383 K400 S405 R455 N471 Q472
Binding residue
(residue number reindexed from 1)		L242 S257 R258 K275 S280 R330 N346 Q347
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0016987 sigma factor activity

View graph for
Molecular Function
External links
PDB RCSB:8rec, PDBe:8rec, PDBj:8rec
PDBsum8rec
PubMed38170755
UniProtP06223|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

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