Structure of PDB 8reb Chain M Binding Site BS01

Receptor Information
>8reb Chain M (length=350) Species: 571 (Klebsiella oxytoca) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAGTPSGNGVDYQDDELPVYQGETTQSLQDYLMWQVELTPFTDTDRAIAT
SIVDAVDDTGYLTIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAA
KDLRDCLLIQLSQFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLK
EEVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSD
LQEARWLIKSLESANDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQ
AVEMHESTISRVTTQKYLHSPRGIFELKYFFSSHVNTEGGGEASSTAIRA
LVKKLIAAENPAKPLSDSKLTSMLSEQGIMVARRTVAKYRESLSIPPSNQ
Ligand information
>8reb Chain N (length=43) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gctggcacgacttttgcactcgtatatcatgctgttgcacatt
Receptor-Ligand Complex Structure
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PDB8reb Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		L367 S405 R455 N471 Q472
Binding residue
(residue number reindexed from 1)		L245 S283 R333 N349 Q350
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0016987 sigma factor activity

View graph for
Molecular Function
External links
PDB RCSB:8reb, PDBe:8reb, PDBj:8reb
PDBsum8reb
PubMed38170755
UniProtP06223|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

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