Structure of PDB 8re4 Chain M Binding Site BS01

Receptor Information
>8re4 Chain M (length=380) Species: 571 (Klebsiella oxytoca) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAGTPSGNGVDYQDDELPVYQGETTQSLQDYLMWQVELTPFTDTDRAIAT
SIVDAVDDTGYLTIQIEDIVDSIGDDEIGLEEVEAVLKRIQRFDPVGVAA
KDLRDCLLIQLSQFAKETPWLEEARLIISDHLDLLANHDFRTLMRVTRLK
EEVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDVLVRKVNDRWVVELNSD
SLPRLKINQQYAAMGNSARNDADGQFIRSNLQEARWLIKSLESANDTLLR
VSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKL
TSMLSEQGIMVARRTVAKYRESLSIPPSNQ
Ligand information
>8re4 Chain N (length=47) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gctggcacgacttttgcactctaaataatagatcatgctgttgcaca
Receptor-Ligand Complex Structure
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PDB8re4 Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		A310 W328 L367 S379 R383 K400 R455 R456 N471 Q472
Binding residue
(residue number reindexed from 1)		A218 W236 L275 S287 R291 K308 R363 R364 N379 Q380
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001216 DNA-binding transcription activator activity
GO:0003677 DNA binding
GO:0016987 sigma factor activity
Biological Process
GO:0006352 DNA-templated transcription initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:8re4, PDBe:8re4, PDBj:8re4
PDBsum8re4
PubMed38170755
UniProtP06223|RP54_KLEOX RNA polymerase sigma-54 factor (Gene Name=rpoN)

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