Structure of PDB 8jay Chain M Binding Site BS01

Receptor Information
>8jay Chain M (length=448) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPAQFHDQ
LKARLLEHTIPTQILRESTLAWRDFKNTFGAPIRDFSKIEGHLAWTISTA
AYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSKNPQNACCAAQMFLDNGD
GTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQALESYKEQNKSYPKEVFI
HARTRFNDEEWNAFNEVTPKNTNLVGVTITKSKPLKLYKTEGAFPIMRGN
AYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIFIEINKGEAEIQQVLKDI
LALTKLNYNACIYADGEPVTLRFANKIGEILTASTEIKTPPLAFKYYI
Ligand information
>8jay Chain O (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugacggcucuaaucuauuagu
.....................
Receptor-Ligand Complex Structure
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PDB8jay Auto-inhibition and activation of a short Argonaute-associated TIR-APAZ defense system.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		I223 R225 F245 L252 N439 N468 D474 G475 R481 I507
Binding residue
(residue number reindexed from 1)		I164 R166 F186 L193 N380 N409 D415 G416 R422 I448
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8jay, PDBe:8jay, PDBj:8jay
PDBsum8jay
PubMed37932527
UniProtA0A1I7NFD7

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