Structure of PDB 8idy Chain M Binding Site BS01

Receptor Information
>8idy Chain M (length=86) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK
Ligand information
>8idy Chain 8 (length=156) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu
.........................................<<<<<<.<<
.....>>>.....(.<<<......>>.............>>>..)...>>
>....<<....>><<<<<<<<.......>>>>>>>>..............
......
Receptor-Ligand Complex Structure
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PDB8idy Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R20 R21 G23 N57 T59 G60 G62 R63 M64 R65 H66 L67 K68 R72 F74 H76 R79 E80 G81 T82 T83 P84 K87
Binding residue
(residue number reindexed from 1)		R19 R20 G22 N56 T58 G59 G61 R62 M63 R64 H65 L66 K67 R71 F73 H75 R78 E79 G80 T81 T82 P83 K86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
GO:0097371 MDM2/MDM4 family protein binding
GO:1990948 ubiquitin ligase inhibitor activity
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:1901798 positive regulation of signal transduction by p53 class mediator
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8idy, PDBe:8idy, PDBj:8idy
PDBsum8idy
PubMed37491604
UniProtP61927|RL37_HUMAN Large ribosomal subunit protein eL37 (Gene Name=RPL37)

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