Structure of PDB 8gaf Chain M Binding Site BS01

Receptor Information
>8gaf Chain M (length=264) Species: 486 (Neisseria lactamica) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TIEKRYDFVFLFDVQDGNPNGDPDAGNLPRIDPQTGEGLVTDVCLKRKVR
NFIQMTQNDEHHDIFIREKGILNKTEAARQYMCSRYYDIRTFGAVMTTGK
NAGQVRGPVQLTFSRSIDPIMTLEHSITRMAVTNEKDASETGDNRTMGRK
FTVPYGLYRCHGFISTHFAKQTGFSENDLELFWQALVNMFDHDHSAARGQ
MNARGLYVFEHSNNLGDAPADSLFKRIQVVKKDGVEVVRSFDDYLVSVDD
KNLEETKLLRKLGG
Ligand information
>8gaf Chain K (length=43) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guugaaacagggucagcuugccguagguggcaucgcccucguc
...........................................
Receptor-Ligand Complex Structure
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PDB8gaf Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications.
Resolution3.64 Å
Binding residue
(original residue number in PDB)
N21 G22 P24 N28 R31 V44 K47 R48 E69 V115 N121 Q124 R126 I147 T148 R149 M150 R165 R169 S215 R218
Binding residue
(residue number reindexed from 1)
N20 G21 P23 N27 R30 V43 K46 R47 E68 V95 N101 Q104 R106 I127 T128 R129 M130 R145 R149 S195 R198
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043571 maintenance of CRISPR repeat elements

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Biological Process
External links
PDB RCSB:8gaf, PDBe:8gaf, PDBj:8gaf
PDBsum8gaf
PubMed38242128
UniProtD0W8X6

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