Structure of PDB 7xti Chain M Binding Site BS01

Receptor Information
>7xti Chain M (length=64) Species: 460519 (Komagataella phaffii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKQKLETQFTCLFCNHDNSVVCTLDKKNSIGLLECKKCNLSFQAPINSLS
QPIDIYSDWIDACE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7xti Chain M Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7xti Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		C25 C28 C49 C52
Binding residue
(residue number reindexed from 1)		C11 C14 C35 C38
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000993 RNA polymerase II complex binding
GO:0046872 metal ion binding
Biological Process
GO:0006368 transcription elongation by RNA polymerase II
Cellular Component
GO:0005634 nucleus
GO:0008023 transcription elongation factor complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xti, PDBe:7xti, PDBj:7xti
PDBsum7xti
PubMed35981082
UniProtC4QZ45

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