Structure of PDB 7x75 Chain M Binding Site BS01

Receptor Information
>7x75 Chain M (length=131) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPVKGRATRQRAAVSAALQEVEEFRSAQELHDMLKHKGDAVGLTTVYRTL
QSLADAGEVDVLRTAEGESVYRRCSTGDHHHHLVCRACGKAVEVEGPAVE
KWAEAIAAEHGYVNVAHTVEIFGTCADCAGA
Ligand information
>7x75 Chain O (length=84) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caaggcacatgacaacggtgttcagtgccgcgttgcccgataccccctac
ccgtagttgactggcatccgggcgccgggtcgcc
Receptor-Ligand Complex Structure
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PDB7x75 Structural basis of Streptomyces transcription activation by zinc uptake regulator.
Resolution3.45 Å
Binding residue
(original residue number in PDB)		R14 Q33 Y52 E73
Binding residue
(residue number reindexed from 1)		R9 Q28 Y47 E68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:1900376 regulation of secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0032993 protein-DNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7x75, PDBe:7x75, PDBj:7x75
PDBsum7x75
PubMed35871291
UniProtQ9L2H5

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