Structure of PDB 7ttu Chain M Binding Site BS01

Receptor Information
>7ttu Chain M (length=56) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIRGQINKVK
HLVTVE
Ligand information
>7ttu Chain 1 (length=2684) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaguuauuaagggcgcacgguggaugccuuggcacuagaagccgaugaa
ggacguuacuaacgacgauaugcuuuggggagcuguaaguaagcuuugau
ccagagauuuccgaauggggaaacccagcaugaguuaugucauguuaucg
auaugugaauacauagcauaucagaaggcacacccggagaacugaaacau
cuuaguacccggaggaagagaaagaaaauucgauucccuuaguagcggcg
agcgaaacgggaagagcccaaaccaacguugggguuguaggacacucuag
uuacaaaggacgacauuagacgaaucaucuggaaagaugaaucaaagaag
guaauaauccuguagucgaaaauguugucucucuugaguggauccugagu
acgacggagcacgugaaauuccgucggaaucugggaggaccaucuccuaa
ggcuaaauacucucuagugaccgauagugaaccaguaccgugagggaaag
gugaaaagcaccccggaaggggagugaaauagaaccugaaaccgugugcu
uacaaguagucagagcccguuaaugggugauggcgugccuuuuguagaau
gaaccggcgaguuacgauuugaugcaagguuaagcaguaaauguggagcc
guagcgaaagcgagucugaauagggcguuuaguauuuggucguagacccg
aaaccaggugaucuacccuuggucagguugaaguucagguaacacugaau
ggaggaccgaaccgacuuacguugaaaagugagcggaugaacugagggua
gcggagaaauuccaaucgaaccuggagauagcugguucucuccgaaauag
cuuuagggcuagccucaagugaugauuauuggagguagagcacuguuugg
acgagcgaauucagacaaacuccgaaugccaauuaauuuaacuugggagu
cagaacaugggugauaagguccguguucgaaagggaaacagcccagacca
ccagcuaaggucccaaaauauauguuaaguggaaaaggauguggcguugc
cacagagugacacugcgccgaaaauguaccggggcuaaacauauuaccga
agcuguggauugucgacaaugguaggagagcguucuaagggcguugaagc
augaucguaaggacauguggagcgcuuagaagugagaaugccggugugag
uagcgaaagacgggugagaaucccguccaccgauugacuaagguuuccag
aggaaggcucguccgcucuggguuagucggguccuaagcugaggccgaca
ggcguaggcgauggauaacagguugauauuccuguaccaccuauaaucgu
aucgauggggggacgcaguaggauaggcgaagcgugcgauuggauugcac
gucuaagcaguaaggcgcugagcugugauggggagaagaccuucgagucg
uugauuucacacugccgagaaaagccucuagauagaaaauaggugcccgu
accgcaaaccgacacagguagucaagaugagaauucuaaggugagcgagc
gaacucucguuaaggaacucggcaaaaugaccccguaacuucgggagaag
gggugcucuuuaggguuaacgcccagaagagccgcagugaauaggcccaa
gcgacuguuuaucaaaaacacaggucucugcuaaaccguaaggugaugua
uaggggcugacgccugcccggugcuggaagguuaagaggagugguuagcu
ucugcgaagcuacgaaucgaagccccaguaaacggcggccguaacuauaa
cgguccuaagguagcgaaauuccuugucggguaaguuccgacccgcacga
aaggcguaacgauuugggcacugucucaacgagagacucggugaaaucau
aguaccugugaagaugcagguuacccgcgacaggacggaaagaccccgug
gagcuuuacuguagccugauauugaaauucggcuuucuaacccgcaccac
uuaucguggugggagacagugucaggcgggcaguuugacuggggcggucg
ccuccuaaaagguaacggaggcgcucaaagguucccucagaaugguugga
aaucauucauagaguguaaaggcauaagggagcuugacugcgagaccuac
aagucgagcagggucgaaagacggacuuagugauccggugguuccgcaug
gaagggccaucgcucaacggauaaaagcuaccccggggauaacaggcuua
ucucccccaagaguucacaucgacggggagguuuggcaccucgaugucgg
cucaucgcauccuggggcuguagucggucccaaggguugggcuguucgcc
cauuaaagcgguacgcgagcuggguucagaacgucgugagacaguucggu
cccuauccgucgugggcguaggaaauuugagaggagcuguccuuaguacg
agaggaccgggauggacauaccucugguguaccaguugucgugccaacgg
cauagcuggguagcuauguguggacgggauaagugcugaaagcaucuaag
caugaagccccccucaagaugagauuucccaacuucgguuauaagauccc
ucaaagaugaugagguuaauagguucgagguggaagcauggugacaugug
gagcugacgaauacuaaucgaucgaagacuuaau
<<<<<......<<<<<<<<<<<....{[[..[[<<<<<<<[[<<......
<<<<<<.[...((.>>>.....<<<<<<<..<<.))...]..>>.....>
>>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<<
<<<<<<.........>>>>>>>.>>.>>....<<<<<......<<....>
>.......>>>>.>.........<<....>>..<<<<<......<<....
.>>.....>>>>>..(((....<<<<..>>>>......<<<<<.......
........<.<<<<<<<.<<<...<<<<<......>>>>>((......<<
<.....))>>>...>>>...>>>>>>>..>.........>..>>>>....
.<<<<<<<<.........>>>>>>>>......<<<<<..<<<<>>>>>..
)))......]].>>>>>>>.]]...............<<....>>....]
].........<<<<....>>>>.............}....>>>>>>>>>>
>.......<<<<..<<<<......>>>>..>>>>...<.<........>.
>.<<<<<<....<<<<<<<.<<<<<..<<<...<<<.....>>>...>>>
...<<....>>..<<<<.....>>>>.....>>>>>.>>>>>>>..<<.<
...<<<<<<.....<<<<<<<<<..<<<....<<<<<<......>>>>>>
.....>>>...<<<.<<<<<........>>>>>>>>....>>>>>>>>>.
..<<<.....>>>......>>>>>>......>.>>..<<<<<<....<<<
<<....>>>>><<<<<<<<<...<<<<<<<<<.....<<<...<<<<<<<
<........>>>>>>>>..>>.>.....>>>>.>>>>>..>>>>>>>.>>
..<<<<<<<<<<......>>>>>>>>>>....<<<......>>>...<<<
<.<<<...<<<(((.....<<<<<<...........<<..<<<<.<.<<.
.......>>.>.>>>>.>>...........))).....>>>>>>.>>>..
.>>>>>>><<<<<..>>>>>....>>>>>><.<<<<<<<.<<......<<
<<<.<<....>>.>>>>>...>>.>>>>>>>..>.....>>>>>><....
..<.....<<<<<<.......>>>>>><<<<....<<<<<.<<...<<<<
<<...<<.....>>.>>>>>>....((<<<<.<<...<<<...<<<....
>>>...>>>...>>...<<<<<........>>>>>))<<<<<<.......
.<<...<<<<....<<<<...<<...<......<<<.........>>>..
.<....<<<<...<<..>>...>>>>.....>..................
.>....>>...>>>>.........>>>>..>>.......>>>>>>>>>>.
.>>.....<<......>>>>>>>.<<<.......>>>..>>>>..<<<<.
...<<<<<<<<.<<...............<<<<<....<<..>>.....>
>>>><<<<<<<.<<<<....>>>>.>>>>>>>............<<<<<<
<<<..<<<.........>>>..<<<<<<<.....<<......>>......
.>>>>>>>.<<<<<.<<<..<<<<<<<..<<<<..<<...<<<<<<.<<.
...>>..>>>>>>...>>..>>>>>>>>>..>>>>><<<<<<.......>
>>>>>........<...........<<<<<<.....>>>>>>.....>..
..>>>>>..>>.>>>>>>>.....>>.>>>>>>>>.>>>>.>.....>..
...<<<<<........>>>>>..<<<<<<<<.(((.[[......<<<<.[
[<<<<..<<<<<.<<<<<<<<..<<<<......>>>>....<<.<<<<<<
.....>>>>>>>>......>>>>>>>>..>>>>>..<<<<.....>>>><
<<<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.....
..>>>>>>.....<<.[.(((>>....>>>>>>>...<<<<..<<<....
..>>>..>>>>.<<<....>>>.>>)))]......<<<<<<<.((..>>>
>..))>>>>>>>.............>>>>..]]>>>>.......<<<<.<
.<<<<<<...<<.......>>...>>>>>>...>>>>.>.......<<<<
<.<<<<<<..<<<<<<<<<......>>>>>>..>>>.<<<<<.....>>>
>>.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>...
.]]..)))>>>>>>>>....<<<<<<<...<<<<..<<<<<<<.......
........>>>>>>>.<<<<<...<<<<...<<<<<<<<<<<....>>>>
>>..>>>>>...>>>>.>>>>>...<<<....<<<<<...........>>
>>>....>>>.>>>>.......>>>>>>>.<<<....>>>....<<<<<<
<<<.......>>>>>....<<<<<<<<.<<<....<<<<<....>>>>>.
..>>>..>>>>>.>>>...>>>>....>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ttu A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid.
Resolution3.0 Å
Binding residue
(original residue number in PDB)
R10 S11 I13 G14 E17 A25 K30 G45 Q46
Binding residue
(residue number reindexed from 1)
R9 S10 I12 G13 E16 A24 K29 G44 Q45
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ttu, PDBe:7ttu, PDBj:7ttu
PDBsum7ttu
PubMed35736238
UniProtP0A0G2|RL30_STAA8 Large ribosomal subunit protein uL30 (Gene Name=rpmD)

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