Structure of PDB 7syg Chain M Binding Site BS01 |
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>7syg Chain 2 (length=1697)
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uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau uaaaucaguuaugguuccuuuggucgcucgacuuggauaacugugguaau ucuagagcuaauacaugccgacgggcgcugacccccuucgcgggggggau gcgugcauuuaucaguggugacucuagauaaccucgggccgaucgcacgc ccggcggcgacgacccauucgaacgucugcccuaucaacuuucgauggua gucgccgugccuaccauggugaccacgggugacggggaaucaggguucga uuccggagagggagccugagaaacggcuaccacauccaaggaaggcagca ggcgcgcaaauuacccacucccgacccggggagguagugacgaaaaauaa caauacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaa uccuuuaacgaggauccauuggagggcaagucuggugccagcagccgcgg uaauuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcuc guaguuggaucuugggagcggccguccccugcucggcgccggcccgaagc guuuacuuugaaaaaauuagaguguucaaagcaggccgccuggauaccgc agcuaggaauaauggaauaggaccgcgguucuauuuuguugguuuucgga acugaggccaugauuaagagggacggccgggggcauucguauugcgccgc uagaggugaaauucuuggaccggcgcaagacggaccagagcgaaagcauu ugccaagaauguuuucauuaaucaagaacgaaagucggagguucgaagac gaucagauaccgucguaguuccgaccauaaacgaugccgaccggcgaugc ggcggcguuauucccaugacccgccgggcagcuuccgggaaaccaaaguc uuuggguuccggggggaguaugguugcaaagcugaaacuuaaaggaauuu ggcgaagggcaccaccaggaguggagccugcggcuuaauuugacucaaca cgggaaaccucacccggcccggacacggacaggauugacagauugauagc ucuuucucgauuccgugggugguggugcauggccguucuuaguuggugga gcgauuugucugguuaauuccgauaacgaacgagacucuggcaugcuaac uaguuacgcgaccccggucggcguaacuucuuagagggacaaguggcguu cagccacccgagauugagcaauaacaggucugugaugcccuuagaugucc ggggcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacg ccggcaggcgcggguaacccguugaaccccauucgugauggggaucgggg auugcaauuauuccccaugaacgaggaauucccaguaagugcgggucaua agcuugcguugauuaagucccugcccuuuguacacaccgcccgucgcuac uaccgauuggaugguuuagugaggcccucggaucggccccgccggggugc ccuggcggagcgcugagaagacggucgaacuugacuaucuagaggaagua aaagucguaacaagguuuccguaggugaaccugcggaaggaucauua |
...<<<<<.[[((((>>>>><<<.<<<<<<...<.<<.........<<<. <<<...<....<<....<<..........>>...>>.>.......<<... .....<<<.<....<<....<<<..........<<.....<<..<..... ..>..>>......>>.........<<<<...<<<<<<....>>>>>>... >>>><<..<<<<<...<......>..>>>>>......>>...<<<<.<<< ...>>>>>>>....>>>...>>..>.>>>.<<<....<<<....<<<<<< <.........>>>>>>>>>>......>>>...<<<.<<<<....>>>>.. ..>>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>> >>>.........<<<...<<<<.....>>>.>>>>......>>.>..... <<<<<<<<<.<<<....>>>..>>>>>>.>>>......<<..<....... ....>..>>.........<<<<<((......<<<<.....<<..))>>.. .....>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<< ...<<<.<<.....<<.<.<..>.>.>>..<<<<<..<<..>>.>>>.>> ..<<<.<<.<.......<<...<.......>.<<<<.>>>>...>>.... ..>.>>...>>>........<.<<.<<<<<<<...............>>> >>>>.>>.>....>>....<<<<<<......<<<<..<<..<<<<<<<<. ..<<<......>>>......>>>>>>>>..>>.......<<....>>... >>>>.....>>>.>>>...>>>...>>.>...<<<<<<<<...<...<<< <.<.....>.>>>>...>>>>>>>>..>.......<<<.<<.<<<..<.< <<<<<.<<<........>>>>>>>>>.>..>>>...<<..))>>...>>. ....>>>.>.>.<<<......<<<<....>>>>....>>>..)))).]]. <...<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........ >>..........<<<<<......<<<<<<.......<<.<<<........ >>>.>>.....>>>>>>...<<.<<<.....<<<<<.....<<<.<<<<. .....>>...<<<......>>>...>>.>>>....<<<...<...<<<<. .<<<<<<<<<<<<..>>>>.>>>>>>>>..>>>>..>.....<<<<<... ..>>>>>........>>>.....>>.>>>.......>>>>>.......>> >>>...>>.>>>>.>>>.....<<.<<<................<<<.<< <<....>>>>.>>>..............>>>.>>..........<.<<<< <..........>>>>>>..........>>>>>.....<<<<<<<<..... ..>>>>>>>>......>>...>>>>>>>..>.......<..<<.<..<<< <.<<....<<<<<<<<.<<<...<<<.<<...<<<<<..<<<<<<<<..> >>>>>>>....>>>>>...>>.>>>...>>>.>>>>>>>>...>>.>>>> ...>.>>...>.....<<<<<<<<<....>>>>>>>>>......... |
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PDB | 7syg Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA |
Resolution | 4.3 Å |
Binding residue (original residue number in PDB) | E7 T15 F17 Y36 N39 I40 K48 K58 K59 N65 S67 I68 R69 R71 K79 M82 Q83 Y92 H94 R97 K98 Y99 K104 R105 H106 K107 N108 E130 R132 P133 L134 S135 K136 T137 R139 F140 A149 K153 |
Binding residue (residue number reindexed from 1) | E5 T13 F15 Y34 N37 I38 K46 K56 K57 N63 S65 I66 R67 R69 K77 M80 Q81 Y90 H92 R95 K96 Y97 K102 R103 H104 K105 N106 E128 R130 P131 L132 S133 K134 T135 R137 F138 A147 K151 |
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Enzyme Commision number |
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