Structure of PDB 7qxb Chain M Binding Site BS01

Receptor Information
>7qxb Chain M (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYN
KRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS
Ligand information
>7qxb Chain B (length=256) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gggugguggccauuuuuugucuaacccuaacugagaagggcguaggcgcc
gugcuuuugcuccccgcgcgcuguuuuucucgcugacuuucagcgggcgg
aaaagccucggccugccgccuuccgagcaaacaaaaaaugucagcugcug
gcccguucgccccgaaccccgccgaggccgcggucggcccggggcuucuc
cggaggcacccacugccaccgcgaagaguugggcucugucagccgcgggu
cucucg
...<.<.<<<<..........................<<<<<<<<<<...
..<<<<<<.....<<<<.<<<<<.......[(((((((((>>>>>.>>>>
>>>>>>....>>>>>>.>>>>..............))).)))))).]..>
>>>>....>...<<<..<<<<<....<..<<<<<.<<<..<<<<<<....
....>>>.>>>...>>>>>>>>..<<<<.....>>>>.....>.>>>>>.
...>>>
Receptor-Ligand Complex Structure
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PDB7qxb Structural basis of human telomerase recruitment by TPP1-POT1.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		S39 V40 Y43 I55 S57 M60
Binding residue
(residue number reindexed from 1)		S4 V5 Y8 I20 S22 M25
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7qxb, PDBe:7qxb, PDBj:7qxb
PDBsum7qxb
PubMed35201900
UniProtB4DR52

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