Structure of PDB 7ccr Chain M Binding Site BS01

Receptor Information
>7ccr Chain M (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYT
EHAKRKTVTAMDVVYALKRQGRTLYGFGG
Ligand information
>7ccr Chain T (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acaggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB7ccr Structural basis for nucleosome-mediated inhibition of cGAS activity.
Resolution4.9 Å
Binding residue
(original residue number in PDB)		P32 R36
Binding residue
(residue number reindexed from 1)		P9 R13
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity

View graph for
Molecular Function
External links
PDB RCSB:7ccr, PDBe:7ccr, PDBj:7ccr
PDBsum7ccr
PubMed33051594
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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