Structure of PDB 6vvx Chain M Binding Site BS01

Receptor Information
>6vvx Chain M (length=159) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IFKVGDTVVYPHHGAALVEAIETRTIKGEQKEYLVLKVAQGDLTVRVPAE
NAEYVGVRDVVGQEGLDKVFQVLRAPHTEEPTNWSRRYKANLEKLASGDV
NKVAEVVRDLWRRDQERGLSAGEKRMLAKARQILVGELALAESTDDAKAE
TILDEVLAA
Ligand information
>6vvx Chain P (length=63) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgcccgcttcggggcaaccctgcgtctaatacaaatccggcaatggagtc
aagaccaggttcg
Receptor-Ligand Complex Structure
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PDB6vvx The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase.
Resolution3.39 Å
Binding residue
(original residue number in PDB)		W85 S121 G123
Binding residue
(residue number reindexed from 1)		W84 S120 G122
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0009303 rRNA transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6vvx, PDBe:6vvx, PDBj:6vvx
PDBsum6vvx
PubMed33199626
UniProtP9WJG3|CARD_MYCTU RNA polymerase-binding transcription factor CarD (Gene Name=carD)

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