Structure of PDB 6tq0 Chain M Binding Site BS01

Receptor Information
>6tq0 Chain M (length=67) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TQIFEDPREFLSHLEEYLRQVGGSEEYWLSQIQNHMNGPAKKWWEFKQGS
VKNWVEFKKEFLQYSEG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6tq0 Structural properties and peptide ligand binding of the capsid homology domains of human Arc.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		Q212 I213 F214 P217 F220 H245 N247 A250 F271 Y274
Binding residue
(residue number reindexed from 1)		Q2 I3 F4 P7 F10 H35 N37 A40 F61 Y64
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0050804 modulation of chemical synaptic transmission
GO:2000969 positive regulation of AMPA receptor activity

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6tq0, PDBe:6tq0, PDBj:6tq0
PDBsum6tq0
PubMed33732907
UniProtQ7LC44|ARC_HUMAN Activity-regulated cytoskeleton-associated protein (Gene Name=ARC)

[Back to BioLiP]