Structure of PDB 5zlu Chain M Binding Site BS01

Receptor Information
>5zlu Chain M (length=155) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARRRRAEVRQLQPDLVYGDVLVTAFINKIMRDGKKNLAARIFYDACKIIQ
EKTGQEPLKVFKQAVENVKPRMEVRSRRVGGANYQVPMEVSPRRQQSLAL
RWLVQAANQRPERRAAVRIAHELMDAAEGKGGAVKKKEDVERMAEANRAY
AHYRW
Ligand information
>5zlu Chain G (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuagauacccggguaguccacgcccuaaacgaug
cgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaagcgc
gccgccuggggaguacggccgcaaggcugaaacucaaaggaauugacggg
ggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaaga
accuuaccaggccuugacaugcuagggaacccgggugaaagccuggggug
cccgcgaggggagcccuagcacaggugcugcauggccgucgucagcucgu
gccgugagguguuggguuaagucccgcaacgagcgcaacccccgccguua
guugccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgg
gaggaaggaggggacgacgucuggucagcauggcccuuacggccugggcg
acacacgugcuacaaugcccacuacaaagcgaugccacccggcaacgggg
agcuaaucgcaaaaaggugggcccaguucggauuggggucugcaacccga
ccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgcggug
aauacguucccgggccuuguacacaccgcccgucacgccaugggagcggg
cucuacccgaagucgccgggagccuacgggcaggcgccgaggguagggcc
cgugacuggggcgaagucguaacaagguagcuguaccggaaggugcggcu
ggaucaccuccuuu
....(((.....<<<<..))).<<<<.<<<<<...<<<<<<.........
.<<<...<<..<<..<<<<<<<<.......>>>>>>>>..>>>>......
.<<.......<<<<<<<...<<...<<<<<<<.<<<<<....<<<<<...
...>>>>>.....>>>>>....<<<<.<<<<<....>>>>>.>>>>...<
<<<...>>>>.>>>>>>>..>>.>>>>>>><<<....<<....<<<<<<<
.......>>>>>>>..>>......>>>..<<<<<<<<....>>>>...>>
>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>...
......<<.<<<....<<<<....>>>>..>>>>>.>.>>>>>...<<<<
......<<<<<..>>>>>.....>>>>....<<<<<........<<<<..
...>>>>..........>>>>>......<<<<<((....<<<<<......
...)).........>>>>>>>>>>..>>>>>>>>>..........<<.(.
.....<<<<...<<<..<<<<<.<<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>....<<<<<<.<...<<<<<<
<....<...<<<....<<<......>>>.......>>>....>.......
...<<....>>.>>>>>>>..>.>>>.>>>...>>>...>>>>....<<<
<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<<<<..<<<<<<<<.......>>>>>>>>...<<...)>>.....>>>>
>>..>>..<<......<<<<....>>>>....>>...>>>>...<<<..<
<<<<<<.<<..<<<<<..<<<<<<<<<<......<<........>>....
......<<<<<<<......<.<...<<..<<<<<........>>>>>...
<<......>>...>>...>.>.<<<.<<<..<<<<<<.......<<<<<.
<<<....>>>..<<<<......>>>>...>>>>>.....<<<<.<<<..<
...<<...<<<.....>>>.>>....>..>>>.....<<<<<....>>>>
>........>>>>.........>>>...>>>>>>>>>...>>>>>>>...
>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>.
.>>....>>>.....>>>>>>>.............<<<<<........>>
>>>............>>>>>.....<<<<<<<..........>>>>>>>.
.....>>...>>>>>>>.>>.>.....<..<<.<.<<<..<<<..<<<<<
<<<<<<<<.....<<<<....<<<....>>>.>>>>....>>>>>>>>>>
>>>..>>>..>>>..>.>>...>.....<<<<.<<<<....>>>>.>>>>
..............
Receptor-Ligand Complex Structure
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PDB5zlu Ribosome protection by antibiotic resistance ATP-binding cassette protein.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
A2 R3 R4 R6 R10 L12 D33 G34 R78 G81 G82 R94 S98 R102 R114 W156
Binding residue
(residue number reindexed from 1)
A1 R2 R3 R5 R9 L11 D32 G33 R77 G80 G81 R93 S97 R101 R113 W155
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5zlu, PDBe:5zlu, PDBj:5zlu
PDBsum5zlu
PubMed29712846
UniProtP17291|RS7_THET8 Small ribosomal subunit protein uS7 (Gene Name=rpsG)

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